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Mus musculus

ABSTRACT: LRP8-Reelin-regulated Neuronal (LRN) Enhancer signature underlying learning and memory formation (RNA-Seq 1)

PROVIDER: PRJNA277760 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1873290.fastq.gz	Fastqsanger.gz
	SRR1873286.fastq.gz	Fastqsanger.gz
	SRR1873287.fastq.gz	Fastqsanger.gz
	SRR1873288.fastq.gz	Fastqsanger.gz
	SRR1873289.fastq.gz	Fastqsanger.gz

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Project description:LRP8-Reelin-regulated Neuronal (LRN) Enhancer signature underlying learning and memory formation

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LRP8-Reelin-regulated Neuronal (LRN) Enhancer signature underlying learning and memory formation (GRO-seq)

Project description:A comprehensive landscape of epigenomic events regulated by the Reelin signaling through activation of specific cohort of cis-regulatory enhancer elements (LRN-enhancers), which involves the proteolytical processing of the LRP8 receptor by the gamma-secretase activity and is required for learning and memory behavior All GRO-Seq experiments were designed to understand the unique signature of LRN-enhancers and to evaluate the transcriptional response to Reelin treatment in neuronal cells.

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