Project description:A comparison of different energetics based techniques for the characterization of two mammalian breast cell lines, MCF-7 a luminal A breast cancer cell line and MCF-10A a normal human breast cell line. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.
Project description:The MCF-10A cells in our laboratory were karyotyped using array CGH. The results were compared against previously published karyotypes for the cell line.
Project description:We report differentially expressed genes by DATS exposure in MCF-10A human epithelial cell line and SK-BR-3 human breast cancer cell line
Project description:4D label-free quantitative lactylproteomics analysis was performed to identify the differentially lactylated proteins between human normal mammary epithelial cell line (MCF 10A) and BC cells (MCF7, T-47D, and MDA-MB-468)
