Project description:This SuperSeries is composed of the following subset Series: GSE32488: Expression profiling of formalin-fixed, paraffin-embedded (FFPE) breast cancer metastases of the lymph node and autopsy tissues [DASL HT-12 samples] GSE32489: Expression profiling of formalin-fixed, paraffin-embedded (FFPE) breast cancer metastases of the lymph node and autopsy tissues [DASL HumanRef-v3 samples] Refer to individual Series
Project description:Bulk RNA sequencing was performed on formalin-fixed paraffin-embedded (FFPE) tumor samples to compare transcriptomic profiles between treatment-sensitive and treatment-resistant breast cancer cases.
Project description:This study evaluates the feasibility of using formalin-fixed paraffin-embedded (FFPE) and fixed fresh (FF) breast carcinoma samples for single-cell RNA sequencing (scRNAseq), highlighting the potential of archival FFPE tissues in clinical research and retrospective studies.
Project description:Genome wide DNA methylation profiling of formalin-fixed paraffin-embedded (FFPE) melanoma tissue samples from patients prior to treatment with anti-PD1 immune checkpoint inhibitor therapy. The MethylationEPIC v1.0 BeadChip array was used to obtain DNA methylation profiles across approximately 850,000 CpGs in bisulfite treated DNAs extracted from formalin-fixed paraffin embedded melanoma tissues prior to treatment with anti-PD1 immune checkpoint inhibitor therapy.