Project description:Purpose: To evaluate transcriptome-wide alterations in CD4+ T cells cultured under Th1-polarizing conditions in the absence of the Ikaros zinc finger transcription factor Eos via RNA-seq analysis.
Project description:Zinc finger transcriptional factor CASZ1b suppresses neuroblastoma growth. We have generated a tetracycline inducible CASZ1b expression neuroblastoma cell line (SY5YtetCASZ1b), in which CASZ1b has been transfected into SY5Y cells and its expression could be induced by treating the cells with tetracycline. Using gene expression profiling assay for the cells treated with tetracycline (Tet+) or without tetracycline (Tet-), we identified CASZ1b target genes and downstream transcriptional pathways in neuroblastoma cells.
2016-03-08 | GSE78927 | GEO
Project description:The zinc finger transcription factor BbSmr1 regulates conidial development
Project description:Genome-wide studies have uncovered multiple independent signals at the RREB1 locus associated with altered type 2 diabetes risk and related glycemic traits. However, little is known about the function of the zinc finger transcription factor RREB1 in glucose homeostasis or how changes in its expression and/or function influences diabetes risk.
Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.
Project description:Comprehensive screens and a universal zinc finger model enable transcription factor reprogramming 2 factor reprogrammingComprehensive screens and a universal zinc finger model enable transcription factor reprogramming
