Project description:To understand the function of the small molecule Dip G, the gene expression profiles of HL-60 cells treated with Dip G were analyzed using the microarray.
Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.
Project description:Venetoclax is a selective BCL-2 inhibitor with antileukemic activity. To investigate the transcriptional alterations induced by Venetoclax in human acute myeloid leukemia cells, HL-60 cells were treated with Venetoclax for 48 h and subjected to whole-transcriptome expression profiling using the GeneChip PrimeView Human Gene Expression Array. HL-60 cells were treated with 9.788 μM Venetoclax for 48 h. HL-60 cells without Venetoclax treatment were used as controls. Total RNA was isolated from control and Venetoclax-treated cells, and biotin-labeled cRNA was prepared and hybridized to PrimeView Human Gene Expression Array chips.
