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Homo sapiens

ABSTRACT: Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells

PROVIDER: PRJNA383725 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5461640.fastq.gz	Fastqsanger.gz
	SRR5461641.fastq.gz	Fastqsanger.gz
	SRR5461642.fastq.gz	Fastqsanger.gz
	SRR5461643.fastq.gz	Fastqsanger.gz
	SRR5461644.fastq.gz	Fastqsanger.gz

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Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells

Project description:Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells was performed in order to determine mechanisms of acquired resistance in the PR1 and PR2 cell lines. NRAS p.Q61K mutation identified in PR1 cells. Upregulation of wild-type EGFR signaling identified in PR2 cells.

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