Project description:To investigate genes regulated by miR-489, gene expression analysis was carried out between control siRNA and miR-489 mimic transfected cells.
Project description:We recently identified a subset of down-regulated miRNAs such as miR-489 and miR-504 in HNSCC. Cell growth inhibitions occurred in miR-489 and miR-504 transfectants compared with the controls, suggesting that both miRNAs function as tumor suppressors. The aims of our expression studies were identification of these miRNAs target genes.
