Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA407374 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR6039999.fastq.gz | Fastqsanger.gz | |||
| SRR6040000.fastq.gz | Fastqsanger.gz | |||
| SRR6040010.fastq.gz | Fastqsanger.gz | |||
| SRR6040001.fastq.gz | Fastqsanger.gz | |||
| SRR6040002.fastq.gz | Fastqsanger.gz |
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Project description:We identified genes expressed in mouse liver that are regulated by Cux2, a highly female-specific liver transcription factor whose expression is regulated by sex-dependent plasma GH patterns. Using adenovirus to overexpress Cux2 (Adeno-Cux2) in male liver, we show that Cux2 represses ~35% of male-biased genes and induces/de-represses ~35% of female-biased genes. Adeno-CMV was used as a control for adenoviral infection. (Published in: TL Conforto et al 2012, Mol Cell Biol. 2012, 32:4611-4627. PubMed PMID: 22966202; PMCID: PMC3486175)
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