Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Clinical bronchoalveolar lavage (BAL) samples

ABSTRACT: Clinical bronchoalveolar lavage (BAL) samples Targeted loci

PROVIDER: PRJNA408304 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6059714.fastq.gz	Fastqsanger.gz
	SRR6058215.fastq.gz	Fastqsanger.gz
	SRR6059715.fastq.gz	Fastqsanger.gz
	SRR6059785.fastq.gz	Fastqsanger.gz
	SRR6058216.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Segmental Allergen Challenge Regulates Gene Expression In Bronchoalveolar Lavage (BAL) Cells From Atopic and Mild Asthmatic Subjects

2013-05-01 | GSE46159 | GEO

Segmental Allergen Challenge Regulates Gene Expression In Bronchoalveolar Lavage (BAL) Cells From Atopic and Mild Asthmatic Subjects

Project description:Segmental allergen challenge increases the percentage of eosinophils in bronchoalveolar lavage (BAL) cells. Mepolizumab, an anti-IL-5 therapeutic antibody, decreases the number of eosinophils in bronchoalveolar lavages (BAL). The use of both procedures allows to define genes that are either expressed by eosinophils or dependent on eosinophil presence in the airways. Cells from Bronchoalveolar lavages (BAL) are obtained by bronchoscopy before (V5) and 48 h after a segmental allergen challenge (V6) in atopic and mild astmatics. This procedure was repeated in the same two subjects 2 months later and 1 month after an injection of mepolizumab (V22 is before challenge and V23 after challenge). Cells were immediately lysed and isolated total RNAs were analyzed using the Human Genome 1.0 ST GeneChip arrays (Affymetrix, Santa Clara, CA).

2013-05-01 | E-GEOD-46159 | biostudies-arrayexpress

RNA-seq analysis of human asthma bronchoalveolar lavage (BAL) cells

Project description:RNA-seq analysis of human asthma bronchoalveolar lavage (BAL) cells

| PRJNA562768 | ENA

Single-cell transcriptional analysis of mouse bronchoalveolar lavage (BAL) cells

Project description:Single-cell transcriptional analysis of mouse bronchoalveolar lavage (BAL) cells

| PRJNA700067 | ENA

Characterization of bronchoalveolar lavage samples from two Be-exposed subjects

Project description:Chronic beryllium disease (CBD) is a metal-induced hypersensitivity disorder characterized by CD4+ T cell alveolitis. Single-cell gene expression profiling of bronchoalveolar lavage (BAL) cells focused on T cells may provide insight into unique subsets of CD4+ T cells, functional pathways, and/or molecules that could potentially be developed into novel therapeutics for treating CBD and other granulomatous lung diseases. To understand the unbiased cellular composition of airway associated CD4+ T cells in subjects with beryllium exposure, we used BAL cells from one beryllium-exposed (BeS) and one CBD subject diagnosed using previously defined criteria, and these two samples comprised the disease cohort.

2022-06-01 | GSE181174 | GEO

bronchoalveolar lavage fluid

Project description:bronchoalveolar lavage fluid Metagenome

| PRJNA449183 | ENA

Gene expression profiling of bronchoalveolar lavage cells preceding a clinical diagnosis of chronic lung allograft dysfunction

Project description:Chronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects. In a nested case control study, 1-year post transplant surveillance bronchoalveolar lavage (BAL) fluid samples were obtained from incipient CLAD (n=9) and CLAD free (n=8) lung transplant recipients. Incipient CLAD cases were diagnosed with CLAD within 2 years, while controls were free from CLAD for at least 4 years following bronchoscopy. Transcription profiles in the BAL cell pellets were assayed with the HG-U133 Plus 2.0 microarray (Affymetrix). Differential gene expression analysis was performed to identify a candidate list of differentially expressed probe sets.

2017-01-04 | E-MTAB-5029 | biostudies-arrayexpress

DNA methylation profiles of cells commonly found in bronchoalveolar lavage

Project description:Genome wide DNA methylation profiling of 4 cell populations purified from paediatic bronchoalveolar lavage samples. The cell types profiled are alveolar macrophages, granulocytes, lymphocytes and alveolar epithelial cells. Fluorescence-activated single cell sorting was used to purify the cell populations of interest using previously described methods (Shanthikumar, AJRCMB, 2020 ;63(2):152-159). Genome wide DNA methylation profiling was performed via the EPICArray. These data can be used for reference based deconvolution of cell proportion of bronchoalveolar lavage samples. DNA extracted from raw BAL (n=6) was also profiled using the EPICArray, allowing for validation of reference based deconvulution.

2021-10-09 | GSE185556 | GEO

Rat Bronchoalveolar Lavage Proteome Changes Following E-cigarette Aerosol Exposures

Project description:Label free quantitative proteomics of bronchoalveolar lavage (BAL) fluid collected from rats exposed to e-cigarette aerosols (humidified air control, PG/VG, PG/VG + Nicotine, or PG/VG + Nicotine + Vanillin)

2023-01-06 | MSV000091015 | MassIVE

bronchoalveolar lavage fluid

Project description:bronchoalveolar lavage fluid Raw sequence reads

| PRJNA1265875 | ENA