Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Long non-coding RNAs and mRNAs profiling during spleen development in pig

ABSTRACT: Long non-coding RNAs and mRNAs profiling during spleen development in pig

OTHER RELATED OMICS DATASETS IN: GSE106381

PROVIDER: PRJNA416652 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6240080_1.fastq.gz	Fastqsanger.gz
	SRR6240080_2.fastq.gz	Fastqsanger.gz
	SRR6240090_1.fastq.gz	Fastqsanger.gz
	SRR6240090_2.fastq.gz	Fastqsanger.gz
	SRR6240081_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

Long non-coding RNAs and mRNAs profiling during spleen development in pig

Project description:We describe a total 222.19 Gb of pig RNA-seq sequences generated from the 18 libraries

2018-02-16 | GSE106381 | GEO

Long non-coding RNAs and mRNAs profiling during spleen development in pig.

Project description:Genome-wide transcriptomic studies in humans and mice have become extensive and mature. However, a comprehensive and systematic understanding of protein-coding genes and long non-coding RNAs (lncRNAs) expressed during pig spleen development has not been achieved. LncRNAs are known to participate in regulatory networks for an array of biological processes. Here, we constructed 18 RNA libraries from developing fetal pig spleen (55 days before birth), postnatal pig spleens (0, 30, 180 days and 2 years after birth), and the samples from the 2-year-old Wild Boar. A total of 15,040 lncRNA transcripts were identified among these samples. We found that the temporal expression pattern of lncRNAs was more restricted than observed for protein-coding genes. Time-series analysis showed two large modules for protein-coding genes and lncRNAs. The up-regulated module was enriched for genes related to immune and inflammatory function, while the down-regulated module was enriched for cell proliferation processes such as cell division and DNA replication. Co-expression networks indicated the functional relatedness between protein-coding genes and lncRNAs, which were enriched for similar functions over the series of time points examined. We identified numerous differentially expressed protein-coding genes and lncRNAs in all five developmental stages. Notably, ceruloplasmin precursor (CP), a protein-coding gene participating in antioxidant and iron transport processes, was differentially expressed in all stages. This study provides the first catalog of the developing pig spleen, and contributes to a fuller understanding of the molecular mechanisms underpinning mammalian spleen development.

| S-EPMC5851557 | biostudies-literature

Genome-wide identification and characterization of long non-coding RNAs and mRNAs in goat tissues infected with PPRV

Project description:We have used RNA-Seq to examine long non-coding RNAs (lncRNAs) and mRNAs from PPRV infected goat tissues (Lung, Spleen and Caecum). Our study reveals the prevalence of lncRNAs in goats, and has identified lncRNAs differentially expressed in different tissues of PPRV (Izatnagar94) infected goats, suggesting its important functions during virus infection.

2020-03-17 | GSE130552 | GEO

Profiling of mRNAs, long chain non-coding RNAs and circular RNAs in gastric cancer tissues and adjacent normal tissues

Project description:Purpose: To investigate the role and mechanism of mRNAs, long chain non-coding RNAs and circular RNAs in gastric cancer. Methods: RNA-seq of ribosomal RNA-depleted total RNA were performed to screen differential expressed mRNAs, long chain non-coding RNAs between paired gastric cancer tissues and adjacent normal tissues.For the linear RNA was digested with 3 U of RNase R per µg of RNA. Results: A total of 83672 mRNAs, 105998 long chain non-coding RNAs, 25441 distinct circRNAs were identified in these samples, and 13929 of these circRNAs were identified as novel circRNAs.

2022-03-15 | GSE193453 | GEO

Long non-coding RNAs and mRNAs expression profilling in human nasopharyngeal carcinoma

Project description:Long non-coding RNAs and mRNAs expression profilling in human nasopharyngeal carcinoma

| PRJNA522988 | ENA

RNA sequencing of circular RNAs, long non-coding RNAs ,and mRNAs in human keloid dermal tissues

Project description:RNA sequencing of circular RNAs, long non-coding RNAs ,and mRNAs in human keloid dermal tissues

| PRJNA878513 | ENA

Long non-coding RNAs and mRNAs profiles in mouse liver development

Project description:Many protein-coding oncofetal genes are highly expressed in murine and human fetal liver and silenced in adult liver. The protein products of these hepatic oncofetal genes have been used as clinical markers for the recurrence of hepatocellular carcinoma (HCC) and as therapeutic targets for HCC. Herein, we examined the expression profiles of long non-coding RNAs (lncRNAs) and mRNAs found in fetal and adult liver in mice.LncRNA-mPvt1 is an oncofetal RNA that was found to promote cell proliferation, cell cycling and the expression of stem cell-like properties of murine cells. Human lncRNA-hPVT1 promotes cell proliferation, cell cycling and the acquisition of stem cell-like properties in HCC cells by stabilizing NOP2 protein. Regulation of the lncRNA-hPVT1/NOP2 pathway may have beneficial effects in the treatment of HCC. We collected mouse fetal livers (E12.5, E14.5, E17.5 days), neonatal murine livers and adult murine livers (8 weeks). The total RNAs recovered from these developmental livers and were used to acquire different expression profiles of mRNAs and lncRNAs.

2014-05-20 | E-GEOD-57824 | biostudies-arrayexpress

Olfactory receptor mRNAs act as selfish non-coding RNAs that enforce transcriptional singularity

Project description:Olfactory receptor mRNAs act as selfish non-coding RNAs that enforce transcriptional singularity

| PRJNA960870 | ENA

Deep sequencing of small RNAs of the pig brain

Project description:Small RNAs have been emerged as gene regulators in variety of biological pathways and functions including physiological stress and anxiety response system. In this study, we profiled and cataloged small non-coding RNAs of the pig brain in three different brain regions; the amygdala, hippocampus and hypothalamus obtained from 20 adult pigs. In addition, the adrenal gland was also included in the analysis.

2020-12-01 | E-MTAB-7499 | biostudies-arrayexpress