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DNA methylation inhibitor in HCT116

ABSTRACT: DNA methylation inhibitor in HCT116

PROVIDER: PRJNA422822 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6384510.fastq.gz	Fastqsanger.gz
	SRR6384520.fastq.gz	Fastqsanger.gz
	SRR6384530.fastq.gz	Fastqsanger.gz
	SRR6384511.fastq.gz	Fastqsanger.gz
	SRR6384521.fastq.gz	Fastqsanger.gz

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ChIP-seq with DNA methylation inhibitor in HCT116

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ChIP-seq with DNA methylation inhibitor in HCT116

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Project description:Genome-wide expression and methylation differences are compared for a normal HCT116 cell line and a derived mutant with altered DNA methylation patterns.

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Project description:We aimed to analyze the relationship between TET1 and aberrant CpG methylation in colorectal cancer (CRC). We established two stable TET1 knockdown clones and negative control clones of HCT116 cells, and carried out DNA methylation analysis with HumanMethylation450 BeadChip.

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