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Gene expression signatures of Naïve vs Revertant CD8 T cells from human cord blood

ABSTRACT: Gene expression signatures of Naïve vs Revertant CD8 T cells from human cord blood

PROVIDER: PRJNA472726 | ENA |

REPOSITORIES: ENA

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Gene expression signatures of Naïve vs Revertant CD8 T cells from human cord blood

Project description:We have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish between naive CD8+ T cells (TN) and the same cells which, after activation and incubation with homeostatic cytokines, had reverted to a naive-like phenotype (TNrev). Three umbilical cord blood samples were used to enrich TN and to produce the respective TNrev. Successive ATAC-Seq analysis showed correlation between degree of chromatin accessibility and gene expression profile for both TN and TNrev cells.

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(1) Murine CD4 T cells: naïve vs peptide treated and naïve vs peptide+LPS treated. (2) Murine CD8 T cells naïve vs HY-specific cells from tolerant mice and naïve vs cells from rejecting mice

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Transcription profiling of wild type, GALT-deficient and GALT-deficient-revertant yeast grown on media with galactose or glucose

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Expression profile of bcl11b-deficient NAÏVE CD8+ T cells versus wild type

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RNA-seq data from two metronidazole resistant and one revertant line derived from Giardia intestinalis line WB

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