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Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]

ABSTRACT: Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]

PROVIDER: PRJNA474735 | ENA |

REPOSITORIES: ENA

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Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]

Project description:This study aimed to characterize the transcriptomes of adult retinal ganglion cells (RGCs). The physiological properties of these cells were characterized first in non-dissociated retinal tissue. With that information recorded, the cells were isolated for transcriptome profiling.

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Genetic signatures of retinal ganglion cells revealed through single cell profiling [dissociated RGC]

Project description:Genetic signatures of retinal ganglion cells revealed through single cell profiling [dissociated RGC]

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Project description:This study aimed to characterize the transcriptomes of adult retinal ganglion cells (RGCs). These cells were isolated through their expression of a TdTomato molecule that would only turn on when Cre was present. Cre was controlled by the Parvalbumin promoter.

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