Project description:In this study, a novel IR-binding protein (IRBP) from Momordica charantia, named as mcIRBP, was identified by analyzing the physical and functional interactions between mcIRBP and IR. The hypoglycemic effect and mechanism of mcIRBP were further evaluated in normal and streptozotocin-induced diabetic mice.
Project description:This project aims to conduct a comprehensive proteomic sequencing analysis of extracellular vesicles (EVs) derived from Momordica charantia, systematically identify the protein composition and abundance characteristics of these EVs, and further explore the potential biological functions and molecular mechanisms of the key differential proteins in regulating cell physiological activities, which lays a theoretical foundation for the development and utilization of bioactive substances derived from Momordica charantia.
2025-12-24 | PXD072381 |
Project description:Multi-omics study uncovered key differences in flavor and nutritional quality among three distinct bitter gourd (Momordica charantia L.) cultivars