Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cellular and viral transcription profiles in Equine Papillomavirus Type 2 positive squamous cell carcinomas

ABSTRACT: Cellular and viral transcription profiles in Equine Papillomavirus Type 2 positive squamous cell carcinomas

PROVIDER: PRJNA509141 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8309230.fastq.gz	Fastqsanger.gz
	SRR8309231.fastq.gz	Fastqsanger.gz
	SRR8309232.fastq.gz	Fastqsanger.gz
	SRR8309233.fastq.gz	Fastqsanger.gz
	SRR8309234.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Cellular and viral transcription profiles in Equine Papillomavirus Type 2 positive squamous cell carcinomas

Project description:Equine Papillomavirus Type 2 (EcPV2) appears to be a causal factor for the development of genital especially penile squamous cell carcinomas (SCC) and as such have an important clinical impact on horses. However, the pathomechanisms associated with this cancer transformation are not known, yet. To analyze the host’s and viral transcriptome in EcPV2 affected horses, tissue samples were collected from horses with EcPV2-positive genital lesions as well as from healthy EcPV2-negative horses. Expression levels of host and viral genes were evaluated by RNA-Seq.

2019-12-03 | GSE123533 | GEO

Lung squamous cell carcinomas & papillary predominant adenocarcinomas

Project description:Protein Co-expression Network-based Profiles Revealed from Laser-microdissected Cancerous Cells of Lung Squamous-Cell Carcinomas

2021-07-19 | PXD027381 | JPOST Repository

Genomic alterations in human papillomavirus positive- and negative conjunctival squamous cell carcinoma

Project description:Evaluate the genomic alterations in human papillomavirus positive and negative conjunctival squamous cell carcinoma, by targeted DNA sequencing of 523 genes frequently altered in cancer

2021-12-01 | PRJEB47801 | EVA

scRNA-sequencing from HPV-positive head and neck squamous cell carcinomas

Project description:scRNA-sequencing from HPV-positive head and neck squamous cell carcinomas

| PRJNA725706 | ENA

Characterizing gene expression patterns in Basal Cell Carcinomas and Squamous Cell Carcinomas

Project description:Characterizing gene expression patterns in Basal Cell Carcinomas and Squamous Cell Carcinomas

| PRJNA515744 | ENA

RNA-Seq of oral squamous cell carcinomas and matched normal tissues

Project description:RNA-Seq was applied to oral squamous cell carcinomas and matched normal oral tissue to measure gene expression patterns and identify examples of allelic imbalance. Oral squamous cell carcinomas (OSCC) and matched normal tissue from 3 patients.

2010-02-25 | E-GEOD-20116 | biostudies-arrayexpress

Investigation of the Epithelial to Mesenchymal Transition (EMT) Process in Equine Papillomavirus-2 (EcPV-2)-Positive Penile Squamous Cell Carcinomas.

Project description:Equine penile squamous cell carcinoma (epSCC) is the most frequent tumor of the external male genitalia, representing 67.5% of equine genital cancers. epSCC is associated with papilloma virus (PV) infection and has been recently proposed as a model for human PV-induced squamous cell carcinomas. It has already been suggested that epSCC might undergo epithelial-to-mesenchymal transition (EMT). This work aims to investigate in detail this process and the possible role of PV oncoproteins in epSCC. For this purpose, 18 penile SCCs were retrospectively selected and tested for both EcPV2 presence and oncoproteins (EcPV2 E6 and EcPV2 E7) expression. Moreover, immunohistochemical EMT characterization was carried out by analyzing the main epithelial markers (E-cadherin, β-catenin, and pan-cytokeratin AE3/AE1), the main mesenchymal markers (N-cadherin and vimentin), and the main EMT-related transcription factors (TWIST-1, ZEB-1). PCR analysis was positive for EcPV2 in 16 out of 18 samples. EMT was investigated in epSCC positive for EcPV2. The immunohistochemistry results suggested the presence of EMT processes in the neoplastic cells at the tumor invasive front. Moreover, the significant upregulation of RANKL, together with BCATN1, LEF1, and FOSL1 genes, might suggest a canonical Wnt pathway activation, similarly to what is reported in human penile squamous cell carcinomas.

| S-EPMC8508821 | biostudies-literature

Transcription profiling of equine fibroblasts transformed with Bovine Paillomarvirus type1 experimentally or from explanted sarcoids compared to control fibroblasts

Project description:Bovine Papillomavirus type 1 (BPV-1) and less commonly BPV-2 are associated with the pathogenesis of common equine skin tumours termed sarcoids. In an attempt to understand the mechanisms by which BPV-1 induces sarcoids, we used gene expression profiling as a screening tool to identify candidates genes implicated in disease pathogenesis. Gene expression profiles of equine fibroblasts transformed by BPV-1 either experimentally or from explanted tumours were compared with control equine fibroblasts to identify genes associated with expression of BPV-1.

2008-07-12 | E-MEXP-1658 | biostudies-arrayexpress

LncRNA Expression Profiling in sinonasal squamous cell carcinomas

Project description:LncRNA Expression Profiling in sinonasal squamous cell carcinomas

| PRJNA577404 | ENA

RNA-Seq of oral squamous cell carcinomas and matched normal tissues

Project description:RNA-Seq was applied to oral squamous cell carcinomas and matched normal oral tissue to measure gene expression patterns and identify examples of allelic imbalance.

2010-02-25 | GSE20116 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data