Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single-cell RNA sequence of ovarian tissues at E16.5, postnatal day 0 (PD0) and postnatal day 3 (PD3) with C57/BL6J mouse

ABSTRACT: Single-cell RNA sequence of ovarian tissues at E16.5, postnatal day 0 (PD0) and postnatal day 3 (PD3) with C57/BL6J mouse

PROVIDER: PRJNA554804 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR9693126_1.fastq.gz	Fastqsanger.gz
	SRR9693126_2.fastq.gz	Fastqsanger.gz
	SRR9693127_1.fastq.gz	Fastqsanger.gz
	SRR9693127_2.fastq.gz	Fastqsanger.gz
	SRR9693128_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Single-cell RNA sequence of ovarian tissues at E16.5, postnatal day 0 (PD0) and postnatal day 3 (PD3) with C57/BL6J mouse

Project description:The ovarian tissues at E16.5, postnatal 0 day (PD0 ) and 3 days (PD3) in mice were collected to perform single-cell RNA sequence (scRNA-seq) in this study. The transcriptome landscape of different cell types contributed to discern the intrinsic mechanism of early folliculogenesis, and the developmental stage-specific germline and somatic cells were defined to reveal their genetic programs along with follicle development as well as their regulative molecules and interaction signals. Synthetically, this single cell transcriptomic map of germ cells and granulosa cells would be deemed as a fundamental genetic programs of primordial follicle assembly in mice.

2020-12-30 | GSE134339 | GEO

Mus musculus strain:C57/BL6J

Project description:Mus musculus strain:C57/BL6J Raw sequence reads

| PRJNA798841 | ENA

Mus musculus strain:C57/BL6j

Project description:Mus musculus strain:C57/BL6j Raw sequence reads

| PRJNA688802 | ENA

Single-cell RNA-seq of the developing C57/BL6 mouse back skin at E13.5, E16.5 and P0

Project description:We performed single-cell RNA seq on C57/BL6 mouse back skin at E13.5, E16.5, and P0 to study embryonic hair follicle development. We analyzed 15,086 single cell transcriptome profiles from E13.5, E16.5 and newborn mice (postnatal day 0, P0) dorsal skin cells across hair follicle induction, organogenesis, cytodifferentiation stage. Based on t-distributed Stochastic Neighbor Embedding (tSNE) clustering, we identified 14 cell clusters from skin cells and delineated their cell identity gene expression profile. By using Monocle pseudotime ordering analysis, we constructed epithelium/dermal cell lineage differentiation trajectory and revealed sequential activation of key regulons involved during embryonic hair follicle morphogenesis. Our findings here provide molecular landscape during hair follicle epithelium/dermal cell lineage fate decisions.

2020-07-01 | GSE131498 | GEO

Mus musculus strain:C57 Bl6J (Charles River)

Project description:Mus musculus strain:C57 Bl6J (Charles River) Raw sequence reads

| PRJNA952594 | ENA

RNA-seq of Wild-type and Math5-/- mouse dLGN (dorsolateral geniculate nucleus) at postnatal day 3, postnatal day 7, postnatal day 14 and postnatal day 23

Project description:RNA-seq of Wild-type and Math5-/- mouse dLGN (dorsolateral geniculate nucleus) at postnatal day 3, postnatal day 7, postnatal day 14 and postnatal day 23

| PRJNA516465 | ENA

Transcription profiling of C57/BL6J mice at various ages post partum vs a common control adult (8 week) testis RNA from the same strain

Project description:Testis RNA from C57/BL6J mice at various ages post partum was compared to a common control consisting of adult (8 week) testis RNA from the same strain. This generates a time course showing the activation of genes on the array across the first wave of spermatogenesis, which can then be correlated with the appearance of specific germ cell types, allowing assignation of unknown genes to differing cell types and charting the evolution of the developing testis transcriptome. Adult testis RNA from six different genetic models of infertility (XXSxrb, mshi, Bax -/-, bs, Bcl-w -/- and azh) were compared to age- and strain-matched normal control testis RNA. These models possess different cellular complements within the testis, which can be interpreted within the framework established by the first wave analysis and used to refine the assignment of genes to cell type.

2004-03-02 | E-MEXP-35 | biostudies-arrayexpress

Maternal administration of probiotics promotes brain development and protects offspring's brain from postnatal inflammatory insults in C57/BL6J mice.

Project description:Neonatal morbidities are associated with long term neurological deficits in life and have also been associated with dysbiosis. We tested whether optimizing the neonate's microbiome through maternal probiotic supplementation can improve offspring's neurodevelopmental outcomes. Maternal LB supplementation, carried out by giving Lactobacillus acidophilus and Bifidobacterium infantis (LB) to pregnant C57/BL6J mice daily from E16 to weaning, significantly suppressed postnatal peripheral proinflammatory insult-induced systemic inflammation and normalized compromised blood-brain barrier permeability and tight junction protein expression in the offspring at pre-weaned age. Maternal LB exposure also regulated markers associated with leukocyte transendothelial migration, extracellular matrix injury and neuroinflammation. The suppressed neuroinflammation by maternal LB supplementation was associated with reduced astrocyte/microglia activation and downregulation of the transcriptional regulators CEBPD and IκBα. Furthermore, maternal LB supplementation promoted neuronal and oligodendrocyte progenitor cell development. Our study demonstrates the efficacy of maternal LB supplementation in modulating systemic and central nervous system inflammation as well as promoting neural/oligodendrocyte progenitor development in the offspring. This evidence suggests that maternal probiotic supplementation may be a safe and effective strategy to improve neurological outcomes in the offspring.

| S-EPMC7235088 | biostudies-literature

Effect of deleting PexRAP/ADHAPR in adipose tissue of chow-fed male C57/BL6J mice

Project description:Effect of deleting PexRAP/ADHAPR in adipose tissue of chow-fed male C57/BL6J mice

| PRJNA947490 | ENA

Effect of volume overload on gene expression of right atrium during postnatal heart development

Project description:To investigate the effect of volume overload (VO) during postnatal right atrium (RA) development, we established the RA VO model by conducting the fistula between abdominal aorta and inferior vena cava (ACF) on postnatal day 7(P7) C57/BL6 mice. We then performed gene expression analysis using data obtained from RNA-seq of RA from VO and sham-operated mice at postnatal day 21 (P21).

2023-10-12 | GSE232594 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data