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RNA expression in WT and Dot1L KO CD8 T cell subsets

ABSTRACT: RNA expression in WT and Dot1L KO CD8 T cell subsets

PROVIDER: PRJNA577714 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10285420.fastq.gz	Fastqsanger.gz
	SRR10285421.fastq.gz	Fastqsanger.gz
	SRR10285422.fastq.gz	Fastqsanger.gz
	SRR10285423.fastq.gz	Fastqsanger.gz
	SRR10285424.fastq.gz	Fastqsanger.gz

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RNA expression in WT and Dot1L KO CD8 T cell subsets

Project description:We studied the role of the histone methyltransferase DOT1L in T cell development and differentiation. Here we generated RNA-seq data from sorted CD8 subpopulations from WT (Lcre+/-) and Dot1L KO (Lcre+/-;Dot1Lfl/fl) mice. This data was to define tissue specific expression signatures and it was compared with H3K79me2 ChIP-seq data from the same subsets.

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