Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gut metagenome

ABSTRACT: Subree CRC Mice

PROVIDER: PRJNA602723 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10953400_1.fastq.gz	Fastqsanger.gz
	SRR10953400_2.fastq.gz	Fastqsanger.gz
	SRR10953500_1.fastq.gz	Fastqsanger.gz
	SRR10953500_2.fastq.gz	Fastqsanger.gz
	SRR10953600_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 652

Similar Datasets

gut metagenome

Project description:CRC IL23

| PRJNA877192 | ENA

mouse gut metagenome

Project description:gut microbiota profiles of mice with or without CRC

| PRJNA748781 | ENA

Gut metagenome

Project description:Scott - CRC Crypts

| PRJNA695246 | ENA

gut metagenome

Project description:P. micra in CRC

| PRJNA766025 | ENA

mouse gut metagenome

Project description:Mayo Mouse CRC Samples

| PRJNA544320 | ENA

human gut metagenome

Project description:Gut microbiota in CRC tissues and surrounding non CRC tissues raw sequence reads

| PRJNA286719 | ENA

human gut metagenome

Project description:Gut microbiota in CRC tissues and surrounding non CRC tissues raw sequence reads

| PRJNA286718 | ENA

Relating human gut metagenome and metaproteome

Project description:Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and shotgun metaproteomics. We found a considerable divergence between genetic potential and functional activity of the human healthy gut microbiota, in spite of a quite comparable taxonomic structure revealed by the two approaches. Investigation of inter-individual variability of taxonomic features revealed Bacteroides and Akkermansia as remarkably conserved and variable in abundance within the population, respectively. Firmicutes-driven butyrogenesis (mainly due to Faecalibacterium spp.) was shown to be the functional activity with the higher expression rate and the lower inter-individual variability in the study cohort, highlighting the key importance of the biosynthesis of this microbial by-product for the gut homeostasis. The taxon-specific contribution to functional activities and metabolic tasks was also examined, giving insights into the peculiar role of several gut microbiota members in carbohydrate metabolism (including polysaccharide degradation, glycan transport, glycolysis and short-chain fatty acid production). In conclusion, our results provide useful indications regarding the main functions actively exerted by the gut microbiota members of a healthy human cohort, and support metaproteomics as a valuable approach to investigate the functional role of the gut microbiota in health and disease.

2017-07-19 | PXD005780 | Pride

human gut metagenome

Project description:Human CRC Gut Microbiota Targeted Locus

| PRJNA168081 | ENA

human gut metagenome

Project description:CRC mucosal microbiota project Targeted loci

| PRJNA399638 | ENA