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Human ESC-based modeling of H3.3G34R-mutant high grade glioma

ABSTRACT: Human ESC-based modeling of H3.3G34R-mutant high grade glioma

PROVIDER: PRJNA615218 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11424500_1.fastq.gz	Fastqsanger.gz
	SRR11424500_2.fastq.gz	Fastqsanger.gz
	SRR11424501_1.fastq.gz	Fastqsanger.gz
	SRR11424501_2.fastq.gz	Fastqsanger.gz
	SRR11424502_1.fastq.gz	Fastqsanger.gz

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Human ESC-based modeling of H3.3G34R-mutant high grade glioma

Project description:H3.3G34R-mutant gliomas are lethal tumors of the cerebral hemispheres, with unknown mechanisms of topographic specificity and tumorigenicity. We developed a human embryonic stem cell (hESC)-based model of H3.3G34R-mutant glioma that recapitulates the anatomical and genetic characteristics of the patient tumors.

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