Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Small RNA libraries from epidermal stem cell (ESC) and fibroblast (Fb) derived exosomes

ABSTRACT: Small RNA libraries from epidermal stem cell (ESC) and fibroblast (Fb) derived exosomes

PROVIDER: PRJNA633535 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11807100.fastq.gz	Fastqsanger.gz
	SRR11807101.fastq.gz	Fastqsanger.gz
	SRR11807102.fastq.gz	Fastqsanger.gz
	SRR11807097.fastq.gz	Fastqsanger.gz
	SRR11807098.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Small RNA libraries from epidermal stem cell (ESC) and fibroblast (Fb) derived exosomes

Project description:We employed high-throughput sequencing to profile the non-coding RNA content of primary ESC and Fb derived exosomes. All 6 libraries were sequenced to a comparable depth (ESC1: 12.3M, ESC2: 14M, ESC3: 12.8M, FB1: 14.7M, FB2: 13.7M, FB3: 12.3M) and exhibited a very low proportion of adapter-only reads or fragments shorter than 17bp (4.4 ± 0.5% ), showing efficient fragment incorporation during library preparation. All libraries had high small RNA content (>50% successfully aligned and assigned to small RNAs). ESC libraries had significantly higher small RNA content (ESC: 84.5 ± 0.005% vs FB: 60.5 ± 0.05%, p<0.05, two-sided Welch’s t-test). ESC samples show remarkably higher proportions of miRNAs (~9-fold higher, p=3.6*10-5 ) and snRNAs (~12-fold higher, p=0.002) compared to Fb. Fibroblasts exhibited higher RPM of reads mapping on lncRNAs (4-fold, p=0.052)

2020-10-29 | GSE150765 | GEO

Project description:FB Metagenome

| PRJNA1078716 | ENA

Enterobacter sp. FB strain:FB

Project description:Enterobacter sp. FB strain:FB Genome sequencing and assembly

| PRJNA266747 | ENA

Both wnt signaling and epidermal stem cell-derived exosomes are involved in epidermal development

Project description:Millions suffer from skin diseases. Functional epidermal stem cells are needed in skin therapy or drug screening in vitro. We obtained functional epidermal stem cells with intact stemness and cell junctions by treating them with wnt3a. Moreover, epidermal stem cell-derived exosomes were useful in epidermal development. Finally, functional epidermal 3D organoids with polarity were cultured using wnt3a and the supernatant derived from epidermal stem cells and fresh medium in a 1:1 ratio. These results provide novel directions for the improvement of skin organoids and their potential in clinical application.

2020-07-14 | PXD020351 |

Bordetella sp. FB-8

Project description:Bordetella sp. FB-8

| PRJNA187096 | ENA

Thiomonas sp. FB-6

Project description:Thiomonas sp. FB-6

| PRJNA178046 | ENA

Project description:Breast milk is a complex liquid that enriched in immunological components and affect the development of the infant immune system. Exosomes, the membranous vesicles of endocytic origin, are ubiquitously in various body fluids which can mediate intercellular communication. MicroRNAs (miRNAs), a well-defined group of non-coding small RNAs, in human breast milk are packaged inside exosomes. Here, we present the identification of miRNAs in human breast milk exosomes using deep sequencing technology. We found that the immune-related miRNAs are enriched in breast milk exosomes, and are resistant to the general harsh conditions. Four small RNA libraries in human breast milk exosomes from four healthy women (30 +/- 0.9 years old, primiparity) when the infant were aged at 60 days were sequenced.

2011-12-21 | E-GEOD-32253 | biostudies-arrayexpress

microRNA profiles of exosomes: Exosomes from Pooled Healthy donors' serum vs. Exosomes from Pooled NPC Patients' serum

Project description:microRNA profiles of Exosomes from Pooled NPC Patients serum comparing Control Exosomes from Healthy donors serum Two-condition experiment, Exosomes from Pooled Healthy donors serum vs. Exosomes from Pooled NPC Patients serum. Biological replicates: 1 Exosomes from Pooled Healthy donors serum, 1 Exosomes from Pooled NPC Patients serum,

2014-05-06 | E-GEOD-57319 | biostudies-arrayexpress

Sporotomaculum syntrophicum strain:FB

Project description:Sporotomaculum syntrophicum strain:FB Genome sequencing and assembly

| PRJNA309719 | ENA

Choanocystis sp. FB-2015

Project description:Choanocystis sp. FB-2015 Transcriptome or Gene expression

| PRJNA293113 | ENA