Project description:Our study focuses on searching for novel genes involved in cholesterol metabolism through genome-wide screening, RNA-seq, proteome and lipidomic.This project maily focus on the proteomics of LDLR and HMGCR double knock out human HepG2 cells.
Project description:To investigate the function of LAPTM4B in the regulation of stemness, we established CD133+ HepG2 cells with or without knocked down LAPTM4B.