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Expression data from EI24 overexpression in ESCC cells

ABSTRACT: Expression data from EI24 overexpression in ESCC cells

PROVIDER: PRJNA646230 | ENA |

REPOSITORIES: ENA

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Expression data from EI24 overexpression in ESCC cells

Project description:Analysis of EC109 cells following overexpression of EI24 and control vector. Etoposide induced 2.4 kb transcript (EI24), also known as p53-induced gene 8 (PIG8), is located on human chromosome 11q23. Serving as a p53 responsive pro-apoptotic factor, EI24 plays a pivotal role in inhibiting cell growth and activating autophagy and is associated with drug resistance. Results provide insight into the role of EI24 in cell proliferation and drug resistance of ESCC cells.

2020-07-15 | GSE154422 | GEO

Expression data from EI24 knockdown in ESCC cells

Project description:Expression data from EI24 knockdown in ESCC cells

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Expression data from EI24 knockdown in ESCC cells

Project description:Analysis of TE-1 cells following knockdown of EI24 and control vector. Etoposide induced 2.4 kb transcript (EI24), also known as p53-induced gene 8 (PIG8), is located on human chromosome 11q23. Serving as a p53 responsive pro-apoptotic factor, EI24 plays a pivotal role in inhibiting cell growth and activating autophagy and is associated with drug resistance. Results provide insight into the role of EI24 in cell proliferation and drug resistance of ESCC cells.

2020-07-15 | GSE154423 | GEO

Role of EI24 in ESCC cells

Project description:Role of EI24 in ESCC cells

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RNA sequencing analysis in ESCC cells with Drp1 overexpression or TFAM deficiency

Project description:Mitochondrial homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical regulator for mitochondrial homeostasis, Drp1 and TFAM are frequently abnormal expression in many cancers and is closely implicated in tumorigenesis. Here, we found that Drp1 high expression or TFAM low expression is correlated with poor overall survival of ESCC patients. However, the underling mechanism by Drp1 or TFAM influence tumor progression is largely unknown, especially in esophageal squamous cell carcinoma (ESCC). To investigate the underling mechanisms of Drp1 overexpression or TFAM deficiency-mediated ESCC progression, transcriptome profiling was performed by RNA sequencing analysis in ESCC cells with Drp1 overexpression or TFAM knockdown.

2022-03-02 | GSE182710 | GEO

Differential protein expression between ESCC and normal tissues

Project description:To understand the difference of protein expression between paired esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues, we collected 10 paired ESCC and normal tissues from surgical resected specimems for high-throughput proteomic experiments. From comparative analysis, the dysregulated signaling pathways in ESCC could be uncovered.

2020-08-11 | PXD019834 | Pride

RNA sequencing analysis in ESCC cells with Drp1 overexpression or TFAM deficiency

Project description:RNA sequencing analysis in ESCC cells with Drp1 overexpression or TFAM deficiency

| PRJNA757454 | ENA

Expression data from NRF3 knockdown or overexpression cells

Project description:Expression data from NRF3 knockdown or overexpression cells

| PRJNA736301 | ENA

MeRIP-sequencing in ESCC cells

Project description:MeRIP-sequencing in ESCC cells

| PRJNA646697 | ENA

Expression data from esophageal squamous cell carcinoma (ESCC)

Project description:We used microarrays to determine global gene expression in primary tumor tissues (ESCC) and matched normal tissues (adjacent normal esophageal mucosa) Paired primary ESCC tumor and normal tissues were compared (n=5).

2009-09-01 | E-GEOD-17351 | biostudies-arrayexpress

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