Ontology highlight
ABSTRACT:
PROVIDER: PRJNA662577 | ENA |
REPOSITORIES: ENA
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Project description:This study evaluated the subgingival proteome of parents with periodontitis and their offspring, thereby assessing signatures of periodontal disease. Forty participants were allocated into four groups (n = 10 per group): parents with periodontitis (PP) and their offspring (CP), and control parents (PC) and their offspring (CC). Periodontal clinical parameters were assessed. Gingival crevicular fluid (GCF) and subgingival biofilm were collected from the same sites. Proteome from GCF were investigated by liquid chromatography-tandem mass spectrometry with data-independent acquisition (DIA-PASEF).
2026-01-23 | PXD064469 | Pride
Project description:Several oral bacterial species were grown anaerobically and fed either glucose or lactate in SHI medium (for method see: Edlund et al., 2013, Edlund et al, 2015 - see http://www.microbiomejournal.com/content/pdf/2049-2618-1-25.pdf & http://www.nature.com/ismej/journal/vaop/ncurrent/full/ismej201572a.html). Biofilm samples for LCMS were collected at different time points from growth wells. After growth was established in SHI medium, biofilms were washed with minimal medium and supplemented with either glucose or lactate (Veillonella species) (see Edlund et al., 2013, Edlund et al., 2015). Samples were collected both after the initial biofilm establishment in SHI medium and after the addition of the supplemented cdm medium. According to gnps network analyses and data sorting exercises: 1) ~10% of this data is reproducible; 2) several of the present masses can also be detected both in SHI and cdm medium. mzXML files for media is not uploaded here (i.e. no media subtraction can be employed using these files only).
2015-06-11 | MSV000079151 | GNPS
Project description:Bacterial DNA was detected in both subgingival and carotid plaque samples. The microbial composition differed between subgingival and carotid plaque communities. Alpha diversity analysis revealed significantly higher diversity in subgingival samples compared to carotid plaques (p = 0.039). Beta diversity analysis, including unweighted UniFrac analysis (p<0.001), linear discriminant analysis with effect size estimation, cladogram-based analysis, and principal component analysis, confirmed marked differences between the subgingival and carotid plaque microbiota. However, the study did reveal overlaps in a few individual cases.
2026-04-01 | GSE308470 | GEO
Project description:Multispecies biofilm from subgingival environment Metagenome
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Project description:Subgingival plaque and peri-implant biofilm
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Project description:Oral isolate grown anaerobically in SHI medium as described for project MassIVE ID: MSV000079151
2015-06-12 | MSV000079158 | MassIVE
Project description:We present here a transcriptional regulator, PA3898, which controls biofilm formation and multidrug efflux-pumps in P. aeruginosa. A mutant of this regulator significantly reduced the ability of P. aeruginosa to produce biofilm in vitro, and affected its in vivo fitness and pathogenesis in Drosophila melanogaster and BALB/c mouse lung infection models. Transcriptome analysis revealed that PA3898 modulates essential virulence genes/pathways, including multidrug efflux-pumps and phenazine biosynthesis.ChIP-seq identified its DNA binding sequences and confirmed PA3898 directly interacts with promoter regions of four genes/operons, two of which are mexAB-oprM and phz2.
2018-09-18 | GSE120082 | GEO
Project description:This study compared the subgingival microbiota of subjects with periodontitis to those with periodontal health using the Human Oral Microbe Identification Microarray (HOMIM).
2011-09-17 | GSE32159 | GEO