Project description:We aim to the investigate the role of tamoxifen in breast cancer progression. LCC2 and MCF-7 cells were used as the resistant and sensitive model.

2018-12-26 | GSE118774 | GEO

Genome wide expression change in LCC2 and MCF-7 cells

Project description:Genome wide expression change in LCC2 and MCF-7 cells

| PRJNA486779 | ENA

ESRP1 knockdown in breast cancer cells

Project description:ESRP1 was knocked down in endocrine resistant LCC2 and LCC9 cells

2019-01-19 | GSE125355 | GEO

lncRNA, mRNA, miRNA and circRNA expression data from MCF-7, LCC2 and LCC9 cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-11-18 | GSE159981 | GEO

Transcriptomic analysis of RNA (mRNA/ lncRNA/ circRNA) expression and epitranscriptomic profiling of N4-acetylcytidine-related RNA (mRNA/ lncRNA/ circRNA) acetylation in renal cortex from mice with ischemia reperfusion injury

Project description:N4-acetylation of cytidine (ac4C) in RNA are crucial for regulating the expression level and promoting the translate efficiency of mRNA. However, epitranscriptomic profiling of ac4C-related RNA (mRNA/ lncRNA/ circRNA) acetylation in renal cortex are largely unknown. Therefore, we profiled the transcriptome-wide ac4C modification in mRNA/ lncRNA/ circRNA in renal cortex from either ischemia reperfusion-acute kidney injury (I/R-AKI) mouse or Sham-operated mouse. At the same time, the expression levels of mRNA/ lncRNA/ circRNA were also evaluated by the sequencing experiment in input group. Therefore, this is an experiment for quantifying both the expression levels and the ac4C modification alterations in mRNA/ lncRNA/ circRNA within renal cortex from I/R-AKI mouse.

2026-01-12 | GSE286507 | GEO

mRNA and lncRNA expression profiles in MCF-7 breast cancer cells stably overexpressing pcDNA3.1-PinX1 and Empty Vector

Project description:To elucidate the molecular mechanism and signaling pathways that PinX1 is involved in, a Human LncRNA Array V2.0 (Arraystar, USA)-based genome wide screen of the alterations in lncRNA and mRNA expression profiles was performed in MCF-7 cells stably overexpressing PinX1. MCF-7 breast cancer cells were transfected with the pcDNA3.1-PinX1 and pcDNA3.1 empty vector and the microarray analysis were performed after the clonal selection of cells with a high expression level.

2013-09-30 | E-GEOD-46756 | biostudies-arrayexpress

A study of differential circRNA and lncRNA expressions in COVID-19-infected peripheral blood

Project description:we found a total of 570 circRNA that have difference, among which 155 are up-regulated and 415 are down-regulated; and 898 lncRNA that have difference, in which 414 are up-regulated and 484 are down-regulated; and 476 mRNA that have difference, in which 98 are up-regulated and 378 are down-regulated. In this work, we sequenced circRNA, lncRNA and mRNA from recurrent COVID-19 patients and healthy people, and compared the differences.

2021-02-11 | GSE166552 | GEO

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