Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Fecal microbiome of children with autism spectrum disorder following probiotic and oxytocin supplementation

PROVIDER: PRJNA675093 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12999906_1.fastq.gz	Fastqsanger.gz
	SRR12999906_2.fastq.gz	Fastqsanger.gz
	SRR12999907_1.fastq.gz	Fastqsanger.gz
	SRR12999907_2.fastq.gz	Fastqsanger.gz
	SRR12999908_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 138

Similar Datasets

Project description:Fecal microbiome of children with autism spectrum disorder, their mothers, and healthy children

| PRJNA687773 | ENA

Gene expression in blood of children with autism spectrum disorder

2008-06-26 | GSE6575 | GEO

Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice

Project description:Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder with complex pathophysiology including both genetic and environmental factors. Recent evidence demonstrates the gut microbiome and its resultant metabolome can influence brain and behavior and have been implicated in ASD. To investigate gene by microbiome interactions in a model for genetic risk of ASD, we utilize mutant mice carrying a deletion of the ASD-associated Shank3 gene (Shank3KO). Shank3KO have altered microbiome composition and function at baseline in addition to social deficits. Further depletion of the microbiome with antibiotics exacerbates social deficits in Shank3KO, and results in transcriptional changes in the frontal cortex. Supplementation with the microbial metabolite acetate leads to reversal of social behavioral phenotypes even in mice with a depleted microbiome, and significantly alters transcriptional regulation in the prefrontal cortex. These results suggest a key role for the gut microbiome and the neuroactive metabolite acetate in regulating ASD-like behaviors.

2023-03-02 | GSE225983 | GEO

Transcription profiling of human blood from children with autism spectrum disorder

Project description:Gene expression in blood of children with autism spectrum disorder (ASD) was studied. Transcriptional profiles were compared with age and gender matched, typically developing children from the general population (GP) or IQ matched children with mental retardation or developmental delay (MR/DD). Experiment Overall Design: Transcriptional profiles were compared with age and gender matched, typically developing children from the general population (GP) or IQ matched children with mental retardation or developmental delay (MR/DD)

2008-10-18 | E-GEOD-6575 | biostudies-arrayexpress

Immune Gene Expression in Monocytes from Autism Spectrum Disorders

Project description:To examine how activation of different toll-like receptors (TLR) impacts gene expression in Autism Spectrum Disorder (ASD), we cultured peripheral blood monocytes from children with ASD, Pervasive Developmental Disorder Not Otherwise Specified (PDDNOS) or Asperger and typically developing children and treated them with either lipoteichoic acid (LTA) or lipopolysaccharide (LPS) to activate LTR2 or 4 respectively. Following 24 hours of stimulation, we then performed RNA sequencing to profile mRNA responses between non-treated (NT), LTA and LPS treated samples for each diagnosis (control or ASD).

2021-12-17 | GSE140702 | GEO

Comparative proteome analysis of the dried blood spot from children with autism spectrum disorder

Project description:Reliable biomarkers that assist in the diagnosis of autism spectrum disorder (ASD) are limited. This study aimed to identify proteins that can differentiate children with ASD from controls.

2025-09-17 | PXD063396 | Pride

Project description:Transcriptome sequencing of children with autism spectrum disorder and normal children

| PRJNA903132 | ENA

Project description:Exon sequencing of Autism Spectrum Disorder children with constipation

| PRJNA565477 | ENA

Project description:16S rRNA gene sequence of autism spectrum disorder children

| PRJNA624252 | ENA

Affymetrix CytoScan HD for autism spectrum disorder in children

Project description:Affymetrix CytoScan HD for autism spectrum disorder in children

| PRJNA472953 | ENA