Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Distinct gene expression profiles between preterm- and adult-derived intestinal enteroids exposed to Enterococcus faecalis: A pilot study

ABSTRACT: Distinct gene expression profiles between preterm- and adult-derived intestinal enteroids exposed to Enterococcus faecalis: A pilot study

PROVIDER: PRJNA680035 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13106400.fastq.gz	Fastqsanger.gz
	SRR13106401.fastq.gz	Fastqsanger.gz
	SRR13106402.fastq.gz	Fastqsanger.gz
	SRR13106403.fastq.gz	Fastqsanger.gz
	SRR13106404.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 43

Similar Datasets

Distinct gene expression profiles between preterm- and adult-derived intestinal enteroids exposed to Enterococcus faecalis: A pilot study

Project description:To determine if intestinal derived organoids are different between preterm infants and adults

2021-06-30 | GSE161953 | GEO

INFANT AND ADULT HUMAN INTESTINAL ENTEROIDS ARE MORPHOLOGICALLY AND FUNCTIONALLY DISTINCT

Project description:Intestinal tissues from 3 infants and 3 adults were obtained and the stem cells were isolated to generate enteroids. Enteroids were differentiated for 5 days prior to RNA extraction and sequencing.

2023-08-07 | GSE227205 | GEO

Distinct gene expression profiles between human preterm-derived and adult-derived intestinal organoids exposed to <i>Enterococcus faecalis</i>: a pilot study.

Project description: Not available

| S-EPMC9231289 | biostudies-literature

Bulk RNA-seq of Adult and Fetal Enteroids (Control or Treated with DBZ)

Project description:Bulk RNA sequencing data of both adult and fetal enteroid lines cultured for 1 or 3 days. Conditions include enteroids grown in control basal media and basal media with the notch inhibitor DBZ added.

2022-04-08 | E-MTAB-11619 | biostudies-arrayexpress

Transcriptional response of NGN3 J2 enteroids

Project description:Enteroendocrine cells are hormonal secreting cells in the gut. However, as they comprise <1% of the total epithelial cell population, studies on their response to stimuli have been limited. Chang-Graham, Danhof, Engevik, and Tomaro-Duchesneau et al (PMID 31029854) developed a model enteroid system to overcome this limitation. By driving expression of NGN3 in human jejunal enteroids, their system allows for analysis of hormonal secretion and transcriptional analysis in response to a stimulus. To further characterize these NGN3 enteroids, we performed RNASeq on these enteroids in the induced or uninduced state.

2020-11-04 | GSE138350 | GEO

Transcriptional response of NGN3 J2 enteroids.

2024-07-19 | GSE268681 | GEO

Transcriptomic profiling of the preterm,hyperoxia exposed, rabbit's lung

Project description:Bronchopulmonary dysplasia (BPD) is a multifactorial chronic lung disease of premature neonates. The development of BPD depends on several prenatal and postnatal factors that induce inflammation, altering alveolar growth and pulmonary vascular development. Animal models are essential to investigating the precise molecular pathways leading to BPD. The preterm rabbit combines many advantages of both small (e.g., rodents) and large BPD models (i.e., preterm lambs and baboons). For instance, preterm rabbits display mild-to-moderate respiratory distress at delivery, which, along with ongoing exposure to high oxygen concentration (95% O2), leads to functional and morphological lung changes that resemble the phenotype of human BPD. Nevertheless, the molecular pathways leading to the development of the BPD-like phenotype in this model remain largely ununderstood. We, therefore, aimed to characterize the longitudinal gene expression in the lungs of preterm rabbits continuously exposed to 95% O2 on postnatal days 3, 5, and 7. The longitudinal transcriptomic analysis revealed different expression patterns for several genes and pathways. Over time, extracellular matrix organization and angiogenesis were increasingly downregulated, while apoptosis, RNA processing, and inflammation showed the opposite trend.

2025-04-14 | GSE284417 | GEO

Chicken Enteroids

Project description:Transcriptome of chicken (Gallus gallus) enteroids

| PRJEB37491 | ENA

Enterococcus faecalis biofilm proteome

Project description:The biofilm proteome profile of endodontic and systemic pathogen E. faecalis has been analysed in this study to identify markers associated with its biofilm formation. Strong and weak biofilm forming E. faecalis clinical isolates were compared with two standard ATCC strains of E. faecalis in order to elucidate the biological pathways associated with the biofilm formation capability of E. faecalis.

2018-01-29 | PXD006542 | Pride

Transcriptomic analysis delineates preterm prelabor rupture of membranes from preterm labor in preterm fetal membranes

Project description:We compared fetal membrane tissue from preterm labor deliveries to fetal tissue from preterm labor with preterm prelabor rupture of membranes (PPROM) deliveries to further explore the concept that spontaneous preterm birth can result from the initializing of two separate but overlapping pathological events. Chorioamnion, separated into amnion and chorion, was collected from gestationally age-matched cases and controls within 15 minutes of birth, and analyzed using RNA sequencing. In our study, transcriptome analysis of preterm fetal membranes revealed distinct differentially expressed genes for PPROM, separate from preterm labor. This study is the first to report transcriptome data that reflects the individual pathophysiology of amnion and chorion tissue from PPROM deliveries.

2024-03-13 | GSE243831 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data