Project description:Berberine shows protective effect against AAPH-damaged C17.2 neural stem cells. This study aims to determine the genes regulated by berberine and clarify the possible molecular mechanism underlying the action.
Project description:Berberin has been shown to inhibit HepG2 cell viability. This study aims to determine the genes regulated by berberine and clarify the possible molecular mechanism underlying the action.
Project description:Berberin has been shown to inhibit 3T3L1 preadipocytes differentiation. This study aims to determine the genes regulated by berberine and clarify the possible molecular mechanism underlying the action.
Project description:to explore the pro-carcinogenic property of high-fat diet in AOM/DSS induced CRC mice model and to fathom how berberine inhibits the formation of adenocarcinoma induced by high-fat diet.
Project description:This study aims to identify the underlying crucial proteins and regulatory networks associated with berberine treatment in colon cancer by using both proteomics analyses. Overall,this study shed a light for elucidating the related regulatory signalling pathways and discovering potential targets for berberine in colon cancer.
Project description:Berberine is a natural isoquinoline alkaloid found in Chinese medicinal herbs which is active against a variety of microbial infections. To examine the potential effects of berberine on Shigella flexneri, a whole-genome DNA microarray was constructed and transcriptome analysis of the cellular responses of S.flexneri when exposed to Berberine Chloride (BC) was performed.
Project description:We had three goals to perform this study: compare normal mice and colitis mice,compare berberine effect in normal mice and compare berberine effect in colitis mice