Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: RNA sequencing of Bactrocera tau early embryos

PROVIDER: PRJNA692821 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13452113_1.fastq.gz	Fastqsanger.gz
	SRR13452113_2.fastq.gz	Fastqsanger.gz
	SRR13452114_1.fastq.gz	Fastqsanger.gz
	SRR13452114_2.fastq.gz	Fastqsanger.gz
	SRR13452115_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

The widely conserved microRNA, miR-1-3p, is a male-determining factor in the oriental fruit fly, Bactrocera dorsalis

Project description:We constructed three small RNA libraries from embryos at 5, 6 and 7 post-oviposition (hpo) of Bactrocera dorsalis for deep sequencing. The data analysis revealed 147 known and 103 novel miRNAs from these libraries.

2019-07-04 | GSE117310 | GEO

Transcriptome analysis of the oriental fruit fly Bactrocera dorsalis early embryos

Project description:We constructed three RNA libraries from embryos at 0-1, 2-4 and 5-8 post-oviposition (hpo) of Bactrocera dorsalis for deep sequencing. Using an Illumina HiSeq 2500 platform, we mapped more than 83, 85 and 98 million sequence reads from 0-1, 2-4 and 5-8 hour embryos respectively, and identified a total of 13,489 unigenes. 1683, 3201 and 3134 unigenes showed differential expression between the 0-1 and 2-4 hour embryos, the 0-1 and 5-8 hour embryos, and the 2-4 and 5-8 hour embryos respectively.

2019-01-25 | GSE118472 | GEO

Transcriptome analysis of the oriental fruit fly Bactrocera dorsalis early embryos

Project description:Transcriptome analysis of the oriental fruit fly Bactrocera dorsalis early embryos

| PRJNA485742 | ENA

Single-nucleus RNA sequencing dataset of diverse tissues from wild-type monkey and Tau-P301L transgenic monkey

Project description:Utilizing non-human primates to study the role of human Tau and its related pathologies is logical and important due to their closer similarity to human brain structure and function. In our earlier research, we generated a transgenic cynomolgus monkey model expressing Tau (P301L) through lentiviral infection of monkey embryos. These monkeys exhibited age-dependent neurodegeneration and motor dysfunction. Single-cell RNA sequencing (scRNA-seq) is a powerful and promising technique for elucidating the cellular complexity and pathology across different tissues. However, single-cell data from non-human primate models of Tau pathology are currently nonexistent. In this study, we performed single-nuclei RNA sequencing (snRNA-seq) on the hippocampus, striatum, and spinal cord of Tau (P301L) monkey, providing the first single-cell atlas of multiple tissue regions in a non-human primate model that simulates human tauopathies. This will offer crucial data references for cross-species single-cell level studies of tau and its related pathologies.

2026-01-24 | GSE317176 | GEO

Sex and life experience shape locus coeruleus pretangle tau pathology

Project description:The locus coeruleus (LC) is the earliest site of tau pathology in Alzheimer’s disease (AD), yet how modifiable environmental factors influence its vulnerability, particularly in a sex-specific manner, remains unclear. Using a rat model expressing pseudophosphorylated human tau (htauE14) in the LC, we show that tau accumulation induces anxiety-like behavior, cognitive deficits, and tau spread, shaped by sex and life history. Early-life enrichment attenuated tau propagation, reduced neuroinflammation, and increased hippocampal BDNF expression, while late enrichment reduced anxiety and improved learning. In contrast, late-life stress exacerbated LC degeneration. Single-nucleus RNA sequencing revealed female-biased transcriptional dysregulation in hippocampal excitatory neurons and glia cells following htauE14 expression. Environmental exposures drove distinct cell type-specific transcriptomic signatures: early stress further disrupted mitochondrial and synaptic programs, whereas early enrichment conferred transcriptional stability. These findings position the LC as a sexually dimorphic and environmentally sensitive node of early AD vulnerability and highlight the preventive potential of early-life interventions.

2026-03-18 | GSE306235 | GEO

Early cleavage of preimplantation embryos is regulated by tRNAGln-TTG-derived small RNAs present in mature spermatozoa

Project description:Sperm-derived tsRNAs could act as acquired epigenetic factors and contribute to offspring phenotypes. However, the roles of specific tsRNAs in early embryo development remain to be elucidated. Here, by using pigs as a research model, we probed the tsRNA dynamics during spermatogenesis and sperm maturation, and demonstrated the delivery of tsRNAs from semen-derived exosomes to spermatozoa. By microinjection of the antisense sequence into in vitro fertilized oocytes and subsequent single-cell RNA-sequencing of embryos, we identified a specific functional tsRNA group (Gln-TTGs) that participate in the early cleavage of porcine preimplantation embryos, probably by regulating cell cycle-associated genes. Thus, specific tsRNAs present in mature spermatozoa play significant roles during preimplantation embryo development.

2020-07-13 | PXD019054 | Pride

Bactrocera jarvisi

Project description:Transcriptome sequencing of male and female Bactrocera jarvisi embryos

| PRJNA260466 | ENA

The transcriptional response to the olive fruit fly (Bactrocera oleae) reveals extended differences between tolerant and susceptible olive (Olea europaea L.) varieties

Project description:Comparative profiling of damaged (pool of different stages of fly attack) and control undamaged fruits of cv Ortice and cv Ruveia (Olea europaea L.), characterized by a different tolerance to Bactrocera oleae, generated a comprehensive repertory of transcripts useful to study the genes modulated by Bactrocera oleae attack.

2017-05-06 | GSE81296 | GEO

Ovis aries

Project description:Single cell RNA sequencing of early sheep embryos (PRJCA029376)

| PRJDB36302 | ENA

Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay

Project description:To search for the functional “m6A readers” specifically in the context of Drosophila early embryos, we incubated m6A-modified or unmodified RNA probes with cytosolic lysates from early embryos, and performed immunoprecipitation experiments followed by mass spectrometry analysis. We found that Drosophila FMRP (FMR1) was highly abundant in complexes immuno-precipitated by the m6A-modified probe. We performed data-independent acquisition (DIA) quantitative proteomics on the wild type and fmr1 maternal mutant embryos at multiple developmental stages, including 0-1 h, 2-3 h, and 5-6 h stages. To screen the FMR1-associated partners, we collected the 2–3-hour embryos and performed immunoprecipitation using the anti-Drosophila FMR1 antibody, followed by mass spectrometric analysis.

2021-12-19 | PXD026356 |

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data