Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Kidney organoids are capable of forming Wilms-like tumors, but not teratomas

ABSTRACT: Kidney organoids are capable of forming Wilms-like tumors, but not teratomas

PROVIDER: PRJNA693847 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13498908.fastq.gz	Fastqsanger.gz
	SRR13498909.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Kidney organoids are capable of forming Wilms-like tumors, but not teratomas

Project description:To study safety and stability of kidney organoids, we studied the presence of residual iPSC in the kidney organoids. We also analyzed their potential for malignant transformation in a teratoma assay and following long-term subcutaneous implantation in an immune deficient mouse model.

2021-01-22 | GSE165266 | GEO

Kidney Organoids Are Capable of Forming Tumors, but Not Teratomas.

Project description: Not available

| S-EPMC9216509 | biostudies-literature

Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids

Project description:Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids

| PRJNA780470 | ENA

Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids [bulkRNA-Seq]

Project description:Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids [bulkRNA-Seq]

| PRJNA780481 | ENA

Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids [scRNA-Seq]

Project description:Generation of human iPS cell-derived mesenchymal cells capable of forming alveolar organoids [scRNA-Seq]

| PRJNA780480 | ENA

The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour

Project description:Expression profiling of Wilms tumour samples, which identified molecular signatures of the ureteric bud and collecting duct as well as those of the proximal and distal tubules in triphasic histology tumours. These observations indicate Wilms tumours can arise from a precursor cell capable of generating the entire kidney, such as the cells of the intermediate mesoderm from which both the metanephric mesenchym and ureteric bud are derived.

2017-12-31 | E-MTAB-3516 | biostudies-arrayexpress

Human iPSC derived posterior gut progenitors are expandable and capable of forming gut and liver organoids

Project description:Human iPSC derived posterior gut progenitors are expandable and capable of forming gut and liver organoids

| PRJNA429203 | ENA

Molecular Insights into Non-teratoma-forming Induced Pluripotent Stem Cells

Project description:Human induced pluripotent stem (iPS) cells are capable of differentiating into derivatives of the three embryonic germ layers both in vitro and in vivo. To date the the molecular differences between teratoma-forming cells and non-teratoma-forming cells has not been analysed. A cell line, B1, bears typical ES cell-like morphology, expression of pluripotency-associated genes, and in vitro pluripotency capacity, but fails to form teratomas after subcutaneously injected into immune-deficient mice based on histological analysis. Besides histological analysis, we characterized the tumors derived from line B1, and teratomas derived from bona fida iPS and ES (line H1) cells respectively, using microarray-based gene expression analysis. The expression levels of pluripotency-associated markers in B1 cells were comparable to that in iPS and ES cells, while the complexity of tissue expression commitment was decreased upon spontaneous differentiation of B1 cells as compared to iPS and ES cells. Total RNA obtained from HFF1 (human foreskin fibroblast) cells, line B1, iPS-A4, iPS-B4 and ES (line H1) cells, and their derived tumors in immune-deficient mice.

2012-04-29 | E-GEOD-31970 | biostudies-arrayexpress

Molecular Insights into Non-teratoma-forming Induced Pluripotent Stem Cells

2012-04-30 | GSE31970 | GEO