Liver iNKT transcriptional profiling
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA707550 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR13893206.fastq.gz | Fastqsanger.gz | |||
| SRR13893207.fastq.gz | Fastqsanger.gz | |||
| SRR13893208.fastq.gz | Fastqsanger.gz | |||
| SRR13893209.fastq.gz | Fastqsanger.gz | |||
| SRR13893210.fastq.gz | Fastqsanger.gz |
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Project description:Transcriptional profiling of mouse iNKT cells comparing wild type and Bcl11b deficient cell. The mice were treated with 4 μg of α-galactosylceramide. Goal was to determine the effects of transcription factor Bcl11b removal in iNKT cells. Intraperitoneal treatment with 4 μg of α-Galactosylceramide. Two pair of wild type (BCL11b F/F Vα14 transgenic) and Knock out (BCL11b F/F PLZF-Cre Vα14 transgenic)) mice were treated. Lymphocytes from spleen and liver were enriched and stain with PBS-57 Loaded CD1d tetramer. Pure iNKT cells were collected through cell sorter.
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