Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bulk RNAseq of Sort-purified IV- Primary (1M) or Quaternary (4M) Tcirc (IV- CD69-/CD103-) or Trm (IV- CD69+/CD103+) Memory P14 cells isolated from Spleen or Mediastinal Lymph Nodes

ABSTRACT: Bulk RNAseq of Sort-purified IV- Primary (1M) or Quaternary (4M) Tcirc (IV- CD69-/CD103-) or Trm (IV- CD69+/CD103+) Memory P14 cells isolated from Spleen or Mediastinal Lymph Nodes

PROVIDER: PRJNA722744 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14267800_1.fastq.gz	Fastqsanger.gz
	SRR14267800_2.fastq.gz	Fastqsanger.gz
	SRR14267801_1.fastq.gz	Fastqsanger.gz
	SRR14267801_2.fastq.gz	Fastqsanger.gz
	SRR14267802_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 28

Similar Datasets

Bulk RNAseq of Sort-purified IV- Primary (1M) or Quaternary (4M) Tcirc (IV- CD69-/CD103-) or Trm (IV- CD69+/CD103+) Memory P14 cells isolated from Spleen or Mediastinal Lymph Nodes

Project description:Purpose: The goals of this study are to compare the phenotypic, transcriptomic, trafficking and functional atttibutes of Influenza-experienced circulating or resident memory phenotype cells from the spleen or lung-draining mediastinal lymph nodes. Results: Following read alignment, gene expression profiles were computed using featureCounts. Filtering and visualization of differentially expressed genes with a log2fold change >1.5<-1.5 and a p value of less than 0.05 were identified using Partek GS software and for some figures values from Partek were normalized and displayed using GraphPad Prism. Gene set enrichment and functional assignment were performed in DAVID bioinformatics resources and software from the Broad Institute.

2021-06-28 | GSE172279 | GEO

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

Project description:Tissue-resident memory T cells (TRM) persist locally in non-lymphoid tissues where they provide front-line defense against recurring insults. TRM at barrier surfaces express the markers CD103 and/or CD69 which function to retain them in epithelial tissues. In humans, neither the long-term migratory behavior of TRM nor their ability to re-enter the circulation and potentially migrate to distant tissue sites have been investigated. Using tissue explant cultures, we found that CD4+CD69+CD103+ TRM in human skin can downregulate CD69 and exit the tissue. Additionally, we identified a skin-tropic CD4+CD69-CD103+ population in human lymph and blood that is transcriptionally, functionally and clonally related to the CD4+CD69+CD103+ TRM population in the skin. Using a skin xenograft model, we confirmed that a fraction of the human cutaneous CD4+CD103+ TRM population can re-enter circulation, and migrate to secondary human skin sites where they re-assume a TRM phenotype. Thus, our data challenge current concepts regarding the strict tissue compartmentalization of CD4+ T cell memory in humans.

2019-05-25 | GSE131770 | GEO

Cd69

Project description:Rattus norvegicus Cd69, Cd69 molecule [Source:RGD Symbol;Acc:61318], is differentially expressed in 20 experiment(s);

| ENSRNOG00000056783 | ExpressionAtlas

Cd69

Project description:Rattus norvegicus Cd69, Cd69 molecule [Source:RGD Symbol;Acc:61318], is expressed in 3 baseline experiment(s);

| ENSRNOG00000056783 | ExpressionAtlas

CD69

Project description:Sus scrofa CD69, CD69 molecule [Source:VGNC Symbol;Acc:VGNC:103223], is differentially expressed in 1 experiment(s);

| ENSSSCG00000000653 | ExpressionAtlas

CD69

Project description:Macaca mulatta CD69, CD69 molecule [Source:VGNC Symbol;Acc:VGNC:70776], is expressed in 2 baseline experiment(s);

| ENSMMUG00000015297 | ExpressionAtlas

CD69

Project description:Homo sapiens CD69, CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694], is differentially expressed in 119 experiment(s);

| ENSG00000110848 | ExpressionAtlas

Cd69

Project description:Mus musculus Cd69, CD69 antigen [Source:MGI Symbol;Acc:MGI:88343], is differentially expressed in 77 experiment(s);

| ENSMUSG00000030156 | ExpressionAtlas

CD69

Project description:Oryctolagus cuniculus CD69, CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694], is expressed in 1 baseline experiment(s);

| ENSOCUG00000009055 | ExpressionAtlas

CD69

Project description:Homo sapiens CD69, CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694], is expressed in 30 baseline experiment(s);

| ENSG00000110848 | ExpressionAtlas

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data