Project description:Forsythia suspensa glycoside is a phenylethanoid glycoside extracted from the bark, leaves, flowers, fruits, and seeds of the Oleaceae plant Forsythia suspensa. As a major active ingredient in the Chinese herbal medicine Forsythia suspensa, it has a wide range of pharmacological activities. It not only inhibits various Gram positive and negative bacteria that cause infections, but also has strong antiviral effects. However, the role of Forsythia suspensa glycosides in innate immunity is not yet clear.
Project description:Forsythoside I (FI), a representative caffeoyl phenylethanoid glycoside isolated from Forsythia suspensa, has been previously validated to exert anti-inflammatory and anticancer effects. Nevertheless, research regarding its potential role in cardiovascular diseases, particularly pathological cardiac hypertrophy, and the underlying molecular mechanisms remains largely unknown.
