Elanus leucurus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA771899 | ENA |
REPOSITORIES: ENA
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Project description:Bothrops leucurus is identified as a snake of medical interest in the State of Bahia, Brazil. However, so far, there are no studies that provide a refined mapping of the composition of this venom. The aim of this work was to deepen the knowledge of the toxins from the B. leucurus venom and to isolate and biologically characterize the most abundant toxin, a new basic PLA2 like. Shotgun proteomics approach identified 137 protein hits in B. leucurus venom subdivided into 19 protein families. These findings may enable the improvement of the clinical management of accidents caused by this snakebite.
2021-12-10 | MSV000088552 | MassIVE
Project description:Bothrops spp. is responsible for about 70% of snakebites, causing a diverse and complex pathophysiology, ranging from local to systemic effects in Brazil. Bothrops leucurus is the most common species in the Atlantic range of the Northeast and the main species of medical relevance in the region. Although the influence of the variability of Bothrops venom on the pathology, and the importance of B. leucurus is recognized, the pathophysiological effects involved in snakebite by this species, as well as the reaction of organisms in response to the envenoming have not been explored. We identify the plasma proteins that are affected in terms of abundance during envenoming, and their reflection in the face of biological and pathophysiological processes associated with the local tissue damage caused by snake venom B. leucurus.
2021-05-30 | MSV000087544 | MassIVE