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SARS-COV-2 N protein hijacks host NPM1-snoRNA to enhance rRNA 2’-O-Me modification and facilitate replication

ABSTRACT: SARS-COV-2 N protein hijacks host NPM1-snoRNA to enhance rRNA 2’-O-Me modification and facilitate replication

PROVIDER: PRJNA818624 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18430059.fastq.gz	Fastqsanger.gz
	SRR18430060.fastq.gz	Fastqsanger.gz
	SRR18430061.fastq.gz	Fastqsanger.gz
	SRR18430062.fastq.gz	Fastqsanger.gz
	SRR18430063.fastq.gz	Fastqsanger.gz

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SARS-COV-2 N protein hijacks host NPM1-snoRNA to enhance rRNA 2’-O-Me modification and facilitate replication

Project description:SARS-COV-2 caused COVID-19 has caused unprecedented global health crisis. Coronavirus have developed a variety of mechanisms to interfere host translation machinery to facilitate virus protein production. Here, we conducted Ribometh-seq to explore the effects of ectopic expression of SARS-COV-2 N protein on rRNA 2'-O-me modification profiles of host cells.

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NUCLEAR FATE OF YEAST SNORNA IS DETERMINED BY COTRANSCRIPTIONAL RNT1 CLEAVAGE

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SARS-CoV-2 N protein potentiates host NPM1-snoRNA translation machinery to enhance viral replication.

Project description: Not available

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