Mus spretus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA83951 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR029662.fastq.gz | Fastqsanger.gz | |||
| SRR029663.fastq.gz | Fastqsanger.gz | |||
| SRR029664.fastq.gz | Fastqsanger.gz | |||
| SRR029665.fastq.gz | Fastqsanger.gz | |||
| SRR029666.fastq.gz | Fastqsanger.gz |
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Similar Datasets
Project description:We evaluated the suitability of high-throughput transcriptomics approach to monitor terrestrial ecosystems. Free-living Mus spretus from several polluted sites of Huelva (Andalusia, SW Spain) were compared with mice from Doñana Biological Reserve (“Santa Olalla” lagoon (SOL) used as negative control). As most popular bioindicators, M. spretus is poorly represented in gene databases, therefore limiting the use of genomics in ecotoxicological studies. To solve this problem, we used microarrays produced from mRNAs of M. musculus. Specifically we used the One-Color Gene Expression Platform commercialized by Agilent.
2013-12-31 | GSE33663 | GEO
Project description:We evaluated the suitability of high-throughput transcriptomics approach to monitor terrestrial ecosystems. Free-living Mus spretus from several polluted sites of Huelva (Andalusia, SW Spain) were compared with mice from DoM-CM-1ana Biological Reserve (M-bM-^@M-^\Santa OlallaM-bM-^@M-^] lagoon (SOL) used as negative control). As most popular bioindicators, M. spretus is poorly represented in gene databases, therefore limiting the use of genomics in ecotoxicological studies. To solve this problem, we used microarrays produced from mRNAs of M. musculus. Specifically we used the One-Color Gene Expression Platform commercialized by Agilent. Gene expression in Mus spretus liver was assessed in mice from 5 sites of the Spanish Southwest. Five independent experiments were performed. The arrays were hybridized with labelled cRNA samples made from pooled livers of 9 mice per sampling site. We made 4 technichal repetitions per sample.
2013-12-31 | E-GEOD-33663 | biostudies-arrayexpress
Project description:Illumina RNA-seq data of liver samples from Mus spretus (SPRET/EiJ) and Mus caroli (Caroli/EiJ)
2014-08-20 | E-MTAB-2483 | biostudies-arrayexpress
Project description:Mus musculus x Mus spretus overview
| PRJNA189568 | ENA
Project description:The complexity of environmental systems requires the use of holistic methodologies to conduct studies of contamination effects over individuals who inhabit specific polluted areas. Microarrays are an appropriate tool since they allow the simultaneous expression analysis of thousand genes. As an omic and unbiased technology, it allows for the identification of novel biological responses within certain environmental conditions. A commercial microarray based on probes of the Mus musculus entire genome has been used in order to study transcriptional changes in M. spretus mice exposed to p,p’-DDE, a metabolic by-product of the organochlorine pesticide DDT, whose use is nowadays limited due to the hazardous environmental impact it causes. The success of this approach lies in the high phylogenetic closeness between M. spretus, a species of large environmental interest, whose genome is not sequenced, and the laboratory mouse M. musculus. The results obtained with these heterologous microarrays, verified by qRT-PCR, indicate that the exposed mice to this compound present alterations in their gene expression profiles relative to control animals. Based on the data obtained herein, it can be inferred that mice exposed to p,p’-DDE show alterations in lipids and carbohydrates metabolism, in the immune response, cell cycle control and signaling and molecular transport processes.
2018-06-05 | GSE103767 | GEO
Project description:Environmental pollution assessment using Mus spretus
| PRJNA148635 | ENA
Project description:Mus musculus and Mus spretus sperm methylation
| PRJNA299211 | ENA
Project description:Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion of introgression decreased with geographic distance from the area of sympatry. Introgression was observed on all autosomes for both species, but not on the X-chromosome in M. m. domesticus, consistent with known X-linked hybrid sterility and inviability genes that have been mapped to the M. spretus X-chromosome. Tract lengths were generally short with a few outliers of up to 2.7 Mb. Interestingly, the longest introgressed tracts were in olfactory receptor regions, and introgressed tracts were significantly enriched for olfactory receptor genes in both species, suggesting that introgression may be a source of functional novelty even between species with high barriers to gene flow.
| S-EPMC8784167 | biostudies-literature
Project description:We studied the evolution of alternative splicing in the early stages of species divergence in the house mouse. We sequenced the testis transcriptomes of three Mus musculus subspecies and Mus spretus using Illumina technology. On the basis of a genome-wide analysis of read coverage differences among subspecies, we identified several hundred candidate alternatively spliced regions.
2010-02-28 | E-GEOD-18905 | biostudies-arrayexpress