Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ShRNA-mediated knockdown of PRMT5 gene in LNCaP cells

ABSTRACT: shRNA-mediated knockdown of PRMT5 gene in LNCaP cells

PROVIDER: PRJNA849221 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR19654080.fastq.gz	Fastqsanger.gz
	SRR19654083.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

shRNA-mediated knockdown of PRMT5 gene in LNCaP cells

Project description:We performed shRNA-mediated knockdown of PRMT5 in LNCaP cells via dox-inducible expression system. We sought to compare transcriptome with- and without PRMT5 knockdown across three biological replicates

2025-06-13 | GSE206111 | GEO

shRNA-mediated knockdown of MEP50 gene in LNCaP cells

Project description:shRNA-mediated knockdown of MEP50 gene in LNCaP cells

| PRJNA852249 | ENA

shRNA-mediated knockdown of MEP50 gene in LNCaP cells

Project description:We performed shRNA-mediated knockdown of MEP50 in LNCaP cells via dox-inducible expression system. We sought to compare transcriptome with- and without MEP50 knockdown across three biological replicates

2025-06-23 | GSE206820 | GEO

Testing gene expression changes in VCaP cells following PRMT5 knockdown

Project description:VCaP cells expressing either NTC shRNA or PRMT5 shRNA 1 or shRNA 2 were treated with 100ng/ml doxycycline for 5 days This experiment is designed to see which genes and pathways are modulated by PRMT5 knockdown in VCaP cells VCaP cells were treated with 100ng/ml doxyxycline for 3 days.

2015-04-15 | E-GEOD-65965 | biostudies-arrayexpress

PRMT5 knockdown changes gene expression in prostate cancer cells

Project description:PRMT5 is the major type II protein arginine methyltransferase catalyzing the symmetric dimethylation of arginine. Recent reports have indicated that PRMT5 is overexpressed in multiple cancer types, including prostate. However, the exact contribution of PRMT5 to prostate tumorigenesis is unknown. To explore the functional role of PRMT5 in prostate cancer (PCa), we knocked down PRMT5 by lentiviral shRNAs in both AR-dependent LNCaP cells and AR-independent PC3 cells. Our data suggests that PRMT5 regulates PCa cell biology. To further identify PRMT5-regulated genes in PCa, we performed paired-end RNA-seq analysis in PC3 and LNCaP cells with or without PRMT5-knockdown.

2023-12-25 | GSE117596 | GEO

Testing gene expression changes in VCaP cells following PRMT5 knockdown

2015-04-15 | GSE65965 | GEO

RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells

Project description:We report the pro-leukemic activities of PRMT5 in AML partly via modulating the transcription of key genes. The goal of this experiment is to confirm the changes observed in expression of genes targeted by PRMT5 activities. RNA Deep sequencing was employed to validate and reproduce the changes measured by quantitative reverse transcription polymerase chain reaction (qRTâPCR) techniques. Total RNA samples from MV4-11 cell line (FLT3-ITD AML) following PRMT5 knockdown using specific short hairpin RNA (shRNA) was used to compare gene expression pattern between PRMT5/Knockdown and control (control: MV4-11 cells transduced with scramble control).

2016-05-19 | E-GEOD-75215 | biostudies-arrayexpress

Total RNA-seq of shRNA-mediated TARBP2 knockdown

Project description:Total RNA-seq of shRNA-mediated TARBP2 knockdown

| PRJNA541848 | ENA

Nuclear RNA-seq of shRNA-mediated TARBP2 knockdown

Project description:Nuclear RNA-seq of shRNA-mediated TARBP2 knockdown

| PRJNA541853 | ENA

shRNA-mediated Myc knockdown and shRNA-mediated knockdown of Myc-induced lncRNA KTN1-AS1 in ST486 Burkitt lymphoma cells

Project description:shRNA-mediated Myc knockdown and shRNA-mediated knockdown of Myc-induced lncRNA KTN1-AS1 in ST486 Burkitt lymphoma cells

| PRJNA490714 | ENA