Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing in POLG-iPSC derived brain cells

ABSTRACT: RNA sequencing in POLG-iPSC derived brain cells

PROVIDER: PRJNA853311 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

The single cell transcriptomic profiling in iPSC derived Midbrain Organoid of POLG Disease

Project description:To investigate the transcriptomic profile and molecular mechanisms using single cell RNA sequecning (scRNA-seq) analysis for the iPSC derived midbrain organoids from the patient of POLG Disease

2023-09-28 | GSE241743 | GEO

RNA sequencing in POLG-iPSC derived brain cells

Project description:The pupose of this study is to explore tanalysis to investigate the different phenotypes between homozygous and compound heterozygous genotypes in different brain cell types, including patient-specific fibroblasts, iPSCs and iPSCs-derived neural stem cells (NSCs), and astrocytes.

2022-06-28 | GSE207007 | GEO

RNA-sequencing of iPSC-derived blood-brain barrier cell types across microenvironments

Project description:The blood-brain barrier (BBB) is lined by brain microvascular endothelial cells (BMECs) which regulate transport into and out of the brain. We used human induced pluripotent stem cell (iPSC)-derived cell types to model BBB function within 2D and 3D in vitro models. We compare gene expression between different iPSC-derived cell types, and specifically profile the response of iPSC-derived BMEC-like cells (iBMECs) to differentiation media volume, microenvironmental cues, and cytokines.

2022-01-30 | GSE195519 | GEO

RNA sequencing of human iPSC-derived brain microvascular endothelial cells.

Project description:RNA sequencing of human iPSC-derived brain microvascular endothelial cells.

| PRJEB36836 | ENA

The single cell transcriptomic profiling in iPSC derived Midbrain Organoid of POLG Disease

Project description:The single cell transcriptomic profiling in iPSC derived Midbrain Organoid of POLG Disease

| PRJNA1009590 | ENA

RNA-seq analysis of iPSC-derived brain microvascular endothelial cells following long-term cryopreservation

Project description:We report changes in gene expression from iPSC to iPSC-derived brain microvascular endothelial cells (dhBMECs) and from one-year cryopreservation of dhBMECs.

2020-06-08 | GSE151976 | GEO

E-MTAB-8802

Project description:RNA sequencing of human iPSC-derived brain microvascular endothelial cells.

2025-01-16 | E-MTAB-8802 | ExpressionAtlas

RNA-sequencing of iPSC-derived blood-brain barrier cell types across microenvironments

Project description:RNA-sequencing of iPSC-derived blood-brain barrier cell types across microenvironments

| PRJNA801049 | ENA

RNA-Seq of Aged Polg Mutator Mouse Brains

Project description:We have performed both proteomic and transcriptomic analyses of the brains of one-year old Polg mutator mice. As part of this analysis, we generated RNA-Seq data from RNA isolated from one cerebral hemisphere of these mice. mRNA levels and protein abundance levels were compared in this study. 11 samples of RNA isolated from mouse cerebral hemisphere. 7 Polg D257A/D257A, 1 Polg D257A/WT, and 3 Polg WT/WT. The samples were collected from one-year old male mice.

2015-02-18 | E-GEOD-55188 | biostudies-arrayexpress

mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells

Project description:Purpose: The goals of this study are to compare the transcriptomic profile (mRNA-seq) of HD and control patient iPSC-derived brain microvascular endotheial cells to identify alterations in gene expression. Methods: RNA were isolated from HD and control iPSC-derived brain microvascular endothelial cells. mRNAseq using Illumina TruSeq mRNA PolyA+ v2 lib prep and HiSeq 2500. Statistical difference in mRNA levels were calculated with subsequent GO and pathway analysis. Results: mRNAseq and statistical analysis revealed differentially expressed genes between HD and control iPSC-derived brain microvascular endothelial cells. Conclusions: Our study shows differentially expressed genes between HD and control iPSC-derived brain microvascular endothelial cells, and reveals gene networks that are relevant to the mechanism of HD pathogenesis.

2017-05-16 | GSE97100 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data