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ABSTRACT: APC/min+ mice gastrocnemius muscle sequencing

PROVIDER: PRJNA865152 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR20749320_1.fastq.gz	Fastqsanger.gz
	SRR20749320_2.fastq.gz	Fastqsanger.gz
	SRR20749321_1.fastq.gz	Fastqsanger.gz
	SRR20749321_2.fastq.gz	Fastqsanger.gz
	SRR20749322_1.fastq.gz	Fastqsanger.gz

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Project description:Purpose: Characterize the gene expression profile of gastrocnemius muscle in wild type, ZEB1 and ZEB2 knock out mice subjected to 36 hours of fasting Methods: RNA sequencing of RNA from total gastrocnemius muscle after 36h of fasting from the three genotypes used in this study: ZEB1-control, ZEB1-KO, ZEB2-control, ZEB2-KO. Males and females were used from the four genotype (ZEB1flx/flx, ZEB1flx/flx;HSACre, ZEB2flx/flx, ZEB2flx/flx;HSACre). Results: Knockout of ZEB1 or ZEB2 results in differential gene expression in atrophic gastrocnemius muscle Conclusions: Comparison of wild type, ZEB1 and ZEB2 KO muscles displayed differential gene expression profiles after fasting

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