Project description:Male SHRs and normotensive Wistar-Kyoto(WKY) rats were purchased from Vital River (Vital River Laboratory Animal Technology Co., Ltd, Beijing, China). Briefly, eightteen SHRs aged seven to eight weeks old were randomly assigned to one of three groups: water group (drinking tap water), water containing 333 mg/L or 1g/L TMAO group (TMAO, product number: T1362, Tokyo Chemical Industry, Japan). Six WKY rats of the same age were used as normotensive controls. In this study, WKY rats (n=6), SHR (n=6), and SHR treated with 1g/L TMAO (n=6) were uesd for experiments.
Project description:Nasopharyngeal carcinoma is a common epithelial carcinoma with high occurrence and metastatic rates in Southern China. The assessment of the metastatic potential of NPC is vital for determining prognosis and treatment, and more targeted treatments are needed for NPC.To identify new biomarkers to evaluate metastatic potential of NPC, a comparative genomic expression profiling of NPC tumors and para-carcinoma tissues were assayed by Arraystar human lncRNA array 2.0
Project description:Yellow mutant rainbow trout (YR) is becoming more popular for aquaculture production in China in recent years owing to its excellent meat quality and gorgeous appearance. Although much comparative research has been undertaken on two or three different skin colors of the same species, seldom attentions were focused on the genetic regulation during the developmental process of pigmentation. In this study, the skin transcriptomes in three distinct developmental stages of YR were sequenced to search for genes related to skin pigmentation.
