Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Fungi that inhabits the fur of sloths

PROVIDER: PRJNA876237 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21422738_1.fastq.gz	Fastqsanger.gz
	SRR21422738_2.fastq.gz	Fastqsanger.gz
	SRR21422739_1.fastq.gz	Fastqsanger.gz
	SRR21422739_2.fastq.gz	Fastqsanger.gz
	SRR21422740_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Project description:Antibiotic-producing Micrococcales govern the core microbiome that inhabits the fur of two- and three-toed sloths

| PRJNA804868 | ENA

Exploratory Transcriptomic Analysis of Choloepus didactylus

Project description:Sloths, a group of xenarthran mammals comprised of 6 distinct species, have been the focus of much physiological animal research due to their extremely slow metabolisms, deliberate movements, and their status as a species relatively unchanged for over 26 million years. However, despite all the effort aimed at understanding these unique characteristics, the sloth genome remains largely unexplored. Due to the link between genetics and observed traits, such an investigation could potentially lead to insights regarding the genetic basis of sloth behaviors and characteristics. In this exploratory investigation, we performed genomic and transcriptomic analysis of a female Choloepus didactylus (Linnaeus’s Two-Toed Sloth). Transcriptome analysis of peripheral blood mononuclear cells (PBMCs) showed gene expression levels in two-toed sloths, which are conjectured to be responsible for many of the unique features of two-toed sloths and opens a path towards future exploratory research into specific gene and protein functions tied to the unique characteristics of the sloth species.

2025-03-11 | GSE276969 | GEO

Deciphering the Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli [ChIP-Seq]

Project description:The ferric uptake regulator (Fur) plays a critical role in the transcriptional regulation of iron metabolism in many bacteria. However, the full regulatory potential of Fur beyond iron metabolism remains undefined. Here, we comprehensively reconstructed the Fur transcriptional regulatory network in Escherichia coli K-12 MG1655 in response to iron availability using genome-wide measurements (ChIP-exo and RNA-seq). Polyomic data analysis revealed that a total of 81 genes in 42 transcription units (TUs) are directly regulated by three different modes of Fur regulation, including apo- and holo-Fur activation as well as holo-Fur repression. We showed that Fur connects iron transport and utilization enzymes with negative-feedback loop pairs for iron homeostasis. In addition, direct involvement of Fur in the regulation of DNA synthesis, energy metabolism, and biofilm development was found. These results indicate that Fur exhibits a comprehensive regulatory role affecting many fundamental cellular processes linked to iron metabolism in order to coordinate E. coli responses to the availability of iron. [ChIP-exo]: A total of twelve samples were analyzed. WT and Fur-8-myc tagged cells were cultured in the presense and absence of iron with biological duplicates. To analyze static RNAP binding, rifampicin was also added to the media with biological duplicates. DPD = iron chelator.

2014-09-09 | E-GEOD-54899 | biostudies-arrayexpress

Deciphering the Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli [ChIP-Seq]

2014-09-09 | GSE54899 | GEO

Bacillus subtilis

Project description:Bacillus subtilis CU1065: WT vs fur, fur vs fur fsrA, fur vs fur fbpAB, fur vs fur fbpC, and fur vs fur fbpABC

| PRJNA137241 | ENA

The impact of anaerobiosis on expression of the iron-responsive Fur and RyhB Regulons [ChIP-chip]

Project description:As descirbed in the manuscript The impact of anaerobiosis on expression of the iron-responsive Fur and RyhB Regulons we performed a control ChIP-chip experiment in an E. coli strain lacking the transcription factor Fur to identify regions Fur-independent enrichment.

2015-12-01 | GSE74931 | GEO

Sloth collagen phylogenetics - The living tree sloths Choloepus and Bradypus are the only remaining members of Folivora, a major xenarthran radiation that occupied a wide range of habitats in many parts of the western hemisphere during the Cenozoic, including both continents and the West Indies (Antilles)

Project description:The living tree sloths Choloepus and Bradypus are the only remaining members of Folivora, a major xenarthran radiation that occupied a wide range of habitats in many parts of the western hemisphere during the Cenozoic, including both continents and the West Indies (Antilles). To date, molecular evidence has played only a minor role in folivoran systematics, as most recently-extinct species lived in places not conducive to DNA preservation. Here we utilize collagen sequence information to assess the relationships of tree sloths to a large sample (13 species) of extinct Quaternary folivorans.

2019-06-07 | PXD012859 | Pride

Bacillus subtilis CU1065: fur vs fur fsrA, fur vs fur fbpAB, fur vs fur fbpC, and fur vs fur fbpABC

Project description:Global transcriptional profiling of Bacillus subtilis cells comparing fur mutant to mutants of the iron-sparing response: fur fsrA double mutant, fur fbpAB triple mutant, fur fbpC double mutant, and fur fbpABC quadruple mutant fur vs fur fsrA (fsrA), fur vs fur fbpAB (AB), fur vs fur fbpC (C), and fur vs fur fbpABC (ABC). Each experiemnt (fur vs mutant) was conducted three times using three independent total RNA preparations (2 independent experiement + 1 independent dye swap).

2011-02-19 | E-GEOD-27416 | biostudies-arrayexpress

Palaeoproteomics identifies beaver fur and fur trade in Danish high-status Viking Age burials

Project description:Fur is known from contemporary written sources to have been a key commodity in the Viking Age. Nevertheless, the fur trade has been notoriously difficult to study archaeologically as fur rarely survives in the archaeological record. In Denmark, fur finds are rare and fur in clothing has been limited to a few reports and not recorded systematically. We were therefore given access to fur from six Danish high status graves dated to the Viking Age. The fur was analysed by aDNA and palaeoproteomics methods to identify the species of origin in order to explore the Viking Age fur trade. Endogenous aDNA was not recovered, but fur proteins (keratins) were analysed by MALDI-TOF and LC-MS/MS. We show that Viking Age skin clothing were often composites of several species, showing highly developed manufacturing and material knowledge. For example, fur was produced from wild animals while leather was made of domesticates. Several examples of beaver fur were identified, a species which is not native to Denmark, and therefore indicative of trade. We argue that beaver fur was a luxury commodity, limited to the elite and worn as an easily recognisable indicator of social status.

2022-06-07 | PXD030529 | Pride

gut metagenome

Project description:Sloths Targeted Locus (Loci)

| PRJNA261346 | ENA