Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Acid Whey to Lactate

PROVIDER: PRJNA884981 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21735800_1.fastq.gz	Fastqsanger.gz
	SRR21735800_2.fastq.gz	Fastqsanger.gz
	SRR21735900_1.fastq.gz	Fastqsanger.gz
	SRR21735900_2.fastq.gz	Fastqsanger.gz
	SRR21735801_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 306

Similar Datasets

Project description:Acid whey conversion to lactate isomers

| PRJNA885033 | ENA

Project description:Fermented acid whey (lactate) to caproate

| PRJNA1111158 | ENA

RNA sequencing data of piglet intestinal tissue following different dietary treatments

Project description:Pigs were reared artificially on either milk replacer, milk replacer with liquid creep feed, milk replacer with creep feed + whey, or milk replacer with creep feed + benzoic acid.

2024-12-01 | GSE281198 | GEO

Wenshen Xiaozheng Tang ameliorates endometriosis by interrupting the lactate/H3K9la-mediated crosstalk between ectopic endometrial stromal cells and macrophages

Project description:WXT significantly reduced ectopic lesion volume, alleviated peritoneal adhesions, and decreased the proportion of M2 macrophages in both lesion tissues and peritoneal fluid, along with reduced lactate accumulation and suppressed M2-associated cytokine secretion. Single-cell transcriptomic analysis revealed enhanced glycolytic activity in eESCs and a positive correlation between M2 macrophage polarization and lactate-sensing gene signatures. WXT-containing serum inhibited eESC-derived lactate production, reduced H3K9la levels in macrophages, and blocked lactate-induced M2 polarization. Through UPLC-Q-TOF-MS/MS and molecular docking screening, we identified tormentic acid as a key absorbed component with strong predicted binding to both GLUT1 (a key glycolytic transporter) and p300 (a key regulator of histone lactylation). Tormentic acid reproduced the effects of WXT-containing serum, suppressing lactate production, reducing H3K9la levels, and attenuating M2 polarization. CUT&Tag and ChIP-qPCR further revealed that tormentic acid reduced H3K9la enrichment at the WNT2B promoter and suppressed its expression, defining a lactate-H3K9la-WNT2B axis through which tormentic acid ameliorates endometriosis.

2026-08-05 | GSE342486 | GEO

Determination of WatR binding site in Methylomonas sp. DH-1 after lactate adaptive evolution

Project description:JHM80 strain was obtained by adaptive evolution of Methylomonas sp. DH-1 strain against 8.0 g/L of lactate. The tolerance against lactate of JHM80 was obtained by the overexpression of watR (weak acid tolerance regulator). In order to discover the target genes of WatR, FLAG epitope tag was added to WatR of JHM80 strain and ChIP-seq was performed.

2023-08-08 | GSE206216 | GEO

Expression profiles of microRNA in bovine raw milk exosome and supernatant without exosome [miRNA array]

Project description:We have reported that microRNAs are present in human, bovine, and rat milk whey. Milk whey miRNAs were resistant to acidic condition and to RNase. Thus, milk miRNAs were thought to be present packaged into membrane vesicles like exosome. However, body fluid miRNAs have been reported that there are in different forms. To clarify which miRNAs species are exist in exosome and which species are exist in another form, we used bovine raw milk and purified total RNA from exosome fraction and ultracentrifugated supernatant fraction, and analyzed by miRNA microarray.

2015-03-09 | GSE61976 | GEO

Genome heterogeneity in Lactobacillus helveticus: Rethinking a “niche specialist”*

Project description:Lactobacillus helveticus is a rod-shaped lactic acid bacterium that is widely used in the manufacture of fermented dairy foods and for production of bioactive peptides from milk proteins. Although L. helveticus is commonly associated with milk environments, phylogenetic studies show it is closely related to an intestinal species, Lactobacillus acidophilus, which has been shown to impart probiotic health benefits to humans. This relationship has fueled a prevailing hypothesis that L. helveticus is a highly specialized derivative of L. acidophilus which has adapted to acidified whey. However, L. helveticus has also been sporadically recovered from non-dairy environments, which argues the species may not be as highly specialized as is widely believed. This study employed genome sequence analysis and comparative genome hybridizations to investigate genomic diversity among L. helveticus strains collected from cheese, whey, and whiskey malt, as well as commercial cultures used in manufacture of cheese or bioactive dairy foods. Results revealed considerable variability in gene content between some L. helveticus strains, and indicated the species should not be viewed as a strict dairy-niche specialist. In addition, comparative genomic analyses provided new insight on several industrially and ecologically important attributes of L. helveticus that may facilitate commercial strain selection.

2013-08-16 | GSE23660 | GEO

Whey Protein-based Enteral Nutrition Support to Improve Protein Economy in Surgical Patients

Project description:A prospective, randomized and controlled study is proposed to establish whether an enteral nutrition support regimen based on pressurized whey protein and glucose improves the postoperative utilization of amino acid substrates compared to a drink based on glucose alone. The kinetics of protein metabolism (protein breakdown, protein synthesis and amino acid oxidation) will be investigated using stable isotope methodology before and after surgery in patients undergoing colon resection. Stable isotope infusions will be conducted one week before surgery and on the second postoperative day for two hours in the fasted state and for four hours while sipping the enteral nutrition support regimen. Patients will consume one of two enteral nutrition support regimens consisting of a drink containing either pressurized whey protein and glucose or glucose alone. It is hypothesized that an enteral nutrition support regimen based on pressurized whey protein and glucose promotes positive protein balance through increased protein synthesis or reduced protein breakdown compared to glucose alone.

| 2100821 | ecrin-mdr-crc

Mycobacterium tuberculosis acid growth arrest on priopionate or lactate

Project description:Mycobacterium tuberculosis acid growth arrest on priopionate or lactate

| PRJNA1283112 | ENA

Expression profiles of microRNA in bovine raw milk exosome and supernatant without exosome [mRNA array]

2015-03-09 | GSE61977 | GEO