Project description:Three new physalin steroids, physalin III (1), physalin IV (2), 3-O-methylphysalin X (3), together with five known physalins (4–8) were isolated from the 80% EtOH extract of calyces of Physalis alkekengi var. franchetii. The structures of the new compounds were revealed through 1D and 2D NMR and mass spectroscopic studies. Electronic Supplementary Material Supplementary material is available for this article at 10.1007/s13659-013-0021-z and is accessible for authorized users.