Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ScRNA-Seq analysis of a glioblastoma patient sample after Vortioxetine or DMSO treatment

ABSTRACT: scRNA-Seq analysis of a glioblastoma patient sample after Vortioxetine or DMSO treatment

PROVIDER: PRJNA887805 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR21832248.fastq.gz	Fastqsanger.gz
	SRR21832249.fastq.gz	Fastqsanger.gz
	SRR21832250.fastq.gz	Fastqsanger.gz
	SRR21832251.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

scRNA-Seq analysis of a glioblastoma patient sample after Vortioxetine or DMSO treatment

Project description:Vortioxetine is the neuroactive drug with the highest ex vivo anti-glioblastoma efficacy across patients measured in our study. We used single-cell RNA sequencing (scRNA-seq) to analyze the transcriptomic response to Vortioxetine treatment.

2024-07-29 | GSE214967 | GEO

scRNA-seq of brain glioblastoma sample

Project description:scRNA-seq of brain glioblastoma sample

| PRJNA1141154 | ENA

Gene expression of patient derived xenograft glioblastoma treated with DMSO control or Panobinostat.

Project description:Panobinostat is a non-selective histone deactylase inhibitor which has been approved by FDA for treatment of mutiple myeloma. Whether and how the drug works on glioblastoma remains unclear. Here we treated mice implanted with patient derived xenograft glioblastoma G43 with DMSO or Panobinostat and harvest the tumors for microarray analysis for gene expression results.

2019-01-09 | GSE108957 | GEO

scRNA-Seq analysis of adult glioblastoma patient samples

Project description:scRNA-Seq analysis of adult glioblastoma patient samples

| PRJNA887804 | ENA

scRNA-seq of pediatric glioblastoma patient-derived xenografts

Project description:scRNA-seq of pediatric glioblastoma patient-derived xenografts

| PRJNA482625 | ENA

scRNA-Seq analysis of adult glioblastoma patient samples

Project description:Glioblastoma is the most common type of malignant brain tumor among adults. We used single-cell RNA sequencing (scRNA-seq) to analyze the diversity of glioblastoma cells.

2024-07-25 | GSE214966 | GEO

scRNA-seq of brain glioblastoma sample

Project description:Proneural-mesenchymal transition (PMT) is a phenotypic alteration and contributes to therapeutic resistance and recurrence of glioblastoma (GBM). Macrophages, as a main infiltrating component of tumor immune microenvironment (TIM), can regulate the biological processes of PMT. However, the mechanisms driving this process remain largely unknown. Here, We performed single-cell RNA sequencing (scRNA-seq) (3V3) and Spatial transcriptomics RNA sequencing(stRNA-seq)(1V1) from tumor core and matching tumor periphery samples to discripe the overall landscape of tumor and nontumor cells in gliomas.

2024-12-11 | GSE273274 | GEO

Epigenome analysis of IDH1 mutant and IDH1/2 wild-type patient derived glioblastoma tumorsphere lines.

Project description:The aim of ths study is to compare global methylation status between 1) IDH1 mutant and IDH1/2 wild-type glioblastoma tumorsphere cells and 2) MGG152 (IDH1 mutant) with DMSO and IDH1 inhibitor treatment. Genome wide DNA methylation profiling of patient derived glioblastoma tumorsphere and HT1080 cells. The Illumina Infinium Human DNA methylation Beadchip450 was used to obtain DNA methylation profiles. Bisulphite converted DNA from the 10 samples and one control were hybridised to the Illumina Infinium Human Methylation Beadchip450. Please note that the MGG (in the sample title) represents patient-derived MGH glioblastoma cell lines. Regarding MGG152 samples, sample no.1 is low passage number and used for comparison between IDH1 mt and wild-type. Sample no. 2-4 were used for assessing DNA methylation change after short term or long term IDH1 inhibiting treatment.

2015-09-22 | E-GEOD-73270 | biostudies-arrayexpress

Gene expression of patient derived xenograft glioblastoma treated with DMSO control or Panobinostat.

Project description:Gene expression of patient derived xenograft glioblastoma treated with DMSO control or Panobinostat.

| PRJNA429241 | ENA

scRNA-seq of pediatric glioblastoma patient-derived xenografts

Project description:scRNA-seq of patient-derived xenografts.

2019-03-15 | GSE117599 | GEO