Project description:The target of this project is to investigate the effect of ACOX1 knockout in liver Gene expression profiling analysis were performed using data obtained from RNA-seq of two genotypes mice liver
2024-03-20 | GSE227896 | GEO
Project description:Liver Specific Hsf1 Knockout Mice
Project description:LIF is a pleotropic cytokine and its role in liver ischemia-reperfusion injury (IRI) remains unexplored. Utilizing wildtype (WT) and myeloid cell-specific knockout (KO) mice, we demonstrate that the transcription of LIF is activated in myeloid cells and promotes LIFR-induced STAT3 activation in hepatocytes during liver IRI. To understand the downstream targets of STAT3, we performed ChIP-seq analysis.
2025-12-03 | GSE279970 | GEO
Project description:Transcriptomic analysis for liver from WT, Atg7, Prkar1a, and Atg7 and Prkar1a double knockout mice
Project description:To investigate the role of E4bp4 during non-alcholic liver diseases, we subjected the WT mice and E4bp4 liver specific knockout (E4bp4-LKO) mice to NASH diet for 20 weeks.
Project description:Liver mRNA profiles of one-month-old wild-type (WT) and Dicer liver-specific knockout (Dicer LKO) mice were generated by deep sequencing, in triplicate, using Illumina HiSeq X.
