Project description:tracheal adenoid cystic carcinoma is one kind of non-small-cell lung cancer with limit treatment options. We used single cell RNA sequencing (scRNA-seq) to analyze the molecular characteristic of tracheal adenoid cystic carcinoma, aiming to recognized this disease deeply and provide potential treatment plan in the future.
Project description:Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC) is a recently described rare tumor that is morphologically similar to high grade adenoid cystic carcinoma (ACC), but clinically distinct. We utilized single-cell RNA sequencing (scRNA-seq) to characterize transcriptional heterogeneity in a human HMSC tumor and compared it to published ACC and oropharyngeal squamous cell carcinoma (OPSCC) scRNA-seq datasets.
Project description:To identify the transcriptomic signature of adenoid cystic carcinoma of the lacrimal gland (LGACC), we performed RNA sequencing on LGACC tumor samples and normal lacrimal gland samples.