Ontology highlight
ABSTRACT:
PROVIDER: PRJNA907923 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR22512788_1.fastq.gz | Fastqsanger.gz | |||
| SRR22512788_2.fastq.gz | Fastqsanger.gz | |||
| SRR22512789_1.fastq.gz | Fastqsanger.gz | |||
| SRR22512789_2.fastq.gz | Fastqsanger.gz | |||
| SRR22512790_1.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 5 of 8 |
Similar Datasets
Project description:Genome Sequence of the Yeast Cyberlindnera fabianii (Hansenula fabianii)
| PRJEB6138 | ENA
Project description:NBRP: Genome sequencing of Cyberlindnera fabianii JCM 3601
| PRJDB3616 | ENA
Project description:This is genome-scale metabolic model of Cyberlindnera americana as the representative yeast species for the clade Phaffomycetaceae. This model was generated through homology search using a fungal pan-GEM largely based on Yeast8 for Saccharomyces cerevisiae, in addition to manual curation. This model has been produced by the Yeast-Species-GEMs project from Sysbio (www.sysbio.se). This is model version 1.0.0 accompanying the publication (DOI: 10.15252/msb.202110427), currently hosted on BioModels Database and identified by MODEL2109130008. Further curations of this model will be tracked in the GitHub repository: https://github.com/SysBioChalmers/Yeast-Species-GEMs Models for species of the same clade includes: Cyberlindnera fabianii; Cyberlindnera jadinii; Wickerhamomyces anomalus; Wickerhamomyces ciferrii; Starmera quercuum; Candida stellimalicola; Candida freyschussii; Cyberlindnera mrakii; Cyberlindnera misumaiensis; Candida montana; Barnettozyma californica; Barnettozyma hawaiiensis; Barnettozyma populi; Barnettozyma pratensis; Barnettozyma salicaria; Candida ponderosae; Wickerhamomyces hampshirensis; Wickerhamomyces bovis; Wickerhamomyces alni; Wickerhamomyces sp.; Cyberlindnera petersonii; Wickerhamomyces canadensis; Starmera amethionina; Phaffomyces opuntiae; Phaffomyces antillensis; Phaffomyces thermotolerans; Candida orba; Cyberlindnera saturnus; Cyberlindnera suaveolens; Cyberlindnera xylosilytica; Candida mycetangii; Candida vartiovaarae; Cyberlindnera maclurae; Cyberlindnera americana. These models are available in the zip file. To cite BioModels, please use: V Chelliah et al; BioModels: ten-year anniversary. Nucleic Acids Res 2015; 43 (D1): D542-D548. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to MIT License for more information.
2021-11-01 | MODEL2109130008 | BioModels
Project description:Nyctereutes procyonoides strain:Cyberlindnera jadinii | breed:Cyberlindnera Genome sequencing
| PRJNA851560 | ENA
Project description:Saccharomyces cerevisiae is bradytroph for class B vitamins, it means that yeast cells exhibit slower growth in the absence of an external source of these metabolites. Alleviating these nutritional requirements for optimal growth performance would represent a valuable phenotypic characteristic for industrial strains since this would result in cheaper processes that would also be less susceptible to contaminations. In the present study, suboptimal growth of S. cerevisiae in absence of either pantothenic acid, para-aminobenzoic acid (pABA), pyridoxine, inositol and biotin were corrected by single or double gene overexpression of ScFMS1, ScABZ1/ScABZ2, ScSNZ1/ScSNO1, ScINO1 and the Cyberlindnera fabianii BIO1, respectively. Several strategies were attempted to improve growth of S. cerevisiae CEN.PK113-7D in absence of thiamine, revealing that overexpression of ScTHI4 and ScTHI4/ScTHI5 improved growth up to 83% of the maximum specific growth rate of the reference CEN.PK113-7D in vitamins containing medium. By combining overexpression of solely seven S. cerevisiae genes and the heterologous CfBIO1, the strain IMX2816 was fast-growing at a maximum specific growth rate of 0.33 ± 0.01 h-1 in medium devoid of all vitamins. Secondly, this strain exhibited physiological performances in oxic glucose-limited chemostat cultures at a dilution rate of 0.1 h-1 in absence of vitamins similar to that of the reference strain CEN.PK113-7D grown in fully supplemented medium. These physiological similarities were further emphasized by the limited differences observed in comparative transcriptome analysis from the chemostat culture grown cells that were essentially affecting genes of the class B vitamins biosynthetic pathways. This work paves the way towards construction of the first fast growing vitamin-independent S. cerevisiae strain.
2023-02-21 | GSE225473 | GEO
Project description:Saccharomyces cerevisiae is bradytroph for class B vitamins, it means that yeast cells exhibit slower growth in the absence of an external source of these metabolites. Alleviating these nutritional requirements for optimal growth performance would represent a valuable phenotypic characteristic for industrial strains since this would result in cheaper processes that would also be less susceptible to contaminations. In the present study, suboptimal growth of S. cerevisiae in absence of either pantothenic acid, para-aminobenzoic acid (pABA), pyridoxine, inositol and biotin were corrected by single or double gene overexpression of native FMS1, ABZ1/ABZ2, SNZ1/SNO1, INO1 and the Cyberlindnera fabianii BIO1, respectively. Several strategies were attempted to improve growth of S. cerevisiae CEN.PK113-7D in absence of thiamine, revealing that overexpression of THI4 and THI4/THI5 was able to improve growth up to 83% of the maximum specific growth rate of the reference CEN.PK113-7D in medium including all vitamins. Although the initial aim of this study was to combine all identified mutations in a single strain, the engineered strain IMX2210 only harboured genes to correct biotin, pABA, pantothenate and inositol bradotrophies. Firstly, this strain was fast-growing at a maximum specific growth rate of 0.28 ± 0.01 h-1 in medium devoid of all vitamins. Secondly, this strain exhibited physiological variables in aerobic glucose limited chemostat cultures at a dilution rate of 0.1 h-1 in absence of vitamins similar to that of the reference strain CEN.PK113-7D grown in the same conditions but in a fully supplemented complete medium. These physiological similarities were further emphasized by the limited differences observed in comparative transcriptome analysis from the chemostat culture grown cells that were essentially affecting genes of the class B vitamins biosynthetic pathways. This work paves the way towards construction of the first fast growing vitamin-independent S. cerevisiae strain.
2023-12-01 | GSE191212 | GEO