Project description:A multicenter etiological surveillance study of respiratory tract infections
| PRJNA1165912 | ENA
Project description:Etiology of lower respiratory tract infections in children requiring mechanical ventilation: a multicenter prospective surveillance study incorporating airway metagenomics
| PRJNA748764 | ENA
Project description:Lower respiratory tract virome study
| PRJNA1228250 | ENA
Project description:Pathogen spectrum of lower respiratory tract infections
Project description:Human metapneumovirus (HMPV) is a primary causative agent of acute lower respiratory tract infections. We used single cell RNA-sequencing (scRNA-seq) to assess lung immune profiles in a mouse model of HMPV infection.
Project description:Bovine respiratory epithelial cells have different susceptibility to bovine
respiratory syncytial virus infection. The cells derived from the lower
respiratory tract were significantly more susceptible to the virus than those
derived from the upper respiratory tract. Pre-infection with virus of lower
respiratory tract with increased adherence of P. multocida; this was not the
case for upper tract. However, the molecular mechanisms of enhanced
bacterial adherence are not completely understood. To investigate whether
virus infection regulates the cellular adherence receptor on bovine trachea-,
bronchus- and lung-epithelial cells, we performed proteomic analyses.