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Effect of FDX1 overexpression on gene expression in WSU-DLCL2 cells upon elesclomol stimulation

ABSTRACT: Effect of FDX1 overexpression on gene expression in WSU-DLCL2 cells upon elesclomol stimulation

PROVIDER: PRJNA949166 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR23978665_1.fastq.gz	Fastqsanger.gz
	SRR23978665_2.fastq.gz	Fastqsanger.gz
	SRR23978666_1.fastq.gz	Fastqsanger.gz
	SRR23978666_2.fastq.gz	Fastqsanger.gz
	SRR23978667_1.fastq.gz	Fastqsanger.gz

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Effect of FDX1 overexpression on gene expression in WSU-DLCL2 cells upon elesclomol stimulation

Project description:To investigate the function FDX1 in the regulation of elesclomol (ES)-induced cell death, we established WSU-DLCL2 cell lines in which the full-length coding sequence of FDX1 was overexpressed (FDX1-OE), we then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells (control and FDX1-OE WSU-DLCL2) with or without elsclomol treatment

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Effect of FDX1 overexpression on gene expression in SUDHL-4 cells upon elesclomol stimulation

Project description:To investigate the function FDX1 in the regulation of elesclomol (ES)-induced cell death, we established SUDHL-4 cell lines in which the full-length coding sequence of FDX1 was overexpressed (FDX1-OE), we then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells (control and FDX1-OE SUDHL-4) with or without elsclomol treatment

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Effect of FDX1 overexpression on gene expression in SUDHL-4 cells upon elesclomol stimulation

Project description:Effect of FDX1 overexpression on gene expression in SUDHL-4 cells upon elesclomol stimulation

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AKT1 confers tumor resistance to cuproptosis by phosphorylating FDX1

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Project description:RNA sequencing was performed to characterize transcriptomic changes associated with FDX1 depletion in acute myeloid leukemia cells. Stable FDX1-knockdown MOLM13 cells and corresponding negative-control MOLM13 cells were analyzed using three biologically independent replicates per group. The resulting dataset was used to identify gene-expression changes associated with FDX1 loss.

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