Project description:Oriental Pratincole Glareola maldivarum is a widely distributed water bird species of the Charadriiformes group across Eurasia. In this study, we reveal the mitochondrial genome sequence of the Oriental Pratincole for the first time. The length of the mitochondrial genome is 18,422 bp and contains 2 ribosomal RNA genes, 13 protein coding genes, 22 transfer RNA genes, and 2 D-loop sequences. We further provide a phylogenetic tree showing relationships among Oriental Pratincole and other Charadriiformes species.
Project description:This study aims to investigate the DNA methylation patterns at transcription factor binding regions and their evolutionary conservation with respect to binding activity divergence. We combined newly generated bisulfite-sequencing experiments in livers of five mammals (human, macaque, mouse, rat and dog) and matched publicly available ChIP-sequencing data for five transcription factors (CEBPA, HNF4a, CTCF, ONECUT1 and FOXA1). To study the chromatin contexts of TF binding subjected to distinct evolutionary pressures, we integrated publicly available active promoter, active enhancer and primed enhancer calls determined by profiling genome wide patterns of H3K27ac, H3K4me3 and H3K4me1.
