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ABSTRACT: KPC mice on ketogenic diet versus standard chow diet

PROVIDER: PRJNA961745 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24300504_1.fastq.gz	Fastqsanger.gz
	SRR24300504_2.fastq.gz	Fastqsanger.gz
	SRR24300505_1.fastq.gz	Fastqsanger.gz
	SRR24300505_2.fastq.gz	Fastqsanger.gz
	SRR24300506_1.fastq.gz	Fastqsanger.gz

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Project description:To investigate the translatome in the pancreatic tumor inresponse to ketogenidc diet and the combination of ketogenic diet with an inhibitor targeting eIF4E phosphorylation. We generated pancreatic tumor xenograftmice model, treated mice with regular chow, ketogenic diet or ketogenic diet with eFT508, an inhibitor targeting eIF4E phosphorylation. Then we performed Poly-RNAseq on the tumor isolated from mice upon different treatments.

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